Resistance class 1 integron in clinical methicillin-resistant Staphylococcus aureus strains in southern China, 2001-2006

Z. Xu, L. Li, M. E. Shirtliff, Brian Peters, B. Li, Y. Peng, M. J. Alam, S. Yamasaki, L. Shi

Research output: Contribution to journalArticle

79 Citations (Scopus)

Abstract

As a novel antibiotic resistance determinant, investigation of the occurrence and characteristics of class 1 integron was performed on nosocomial methicillin-resistant Staphylococcus aureus (MRSA) strains sampled during 2001-2006. Seventy-six out of 179 (42.5%) of the tested strains were found to carry class 1 integrons, with four unique arrays of gene cassettes detected. This is the first report of the comprehensive identification and typing of class 1 integrons in clinical MRSA isolates over a 6-year period, representing the first evidence for class 1 integrons as possible antibiotic resistance determinants in clinical MRSA strains.

Original languageEnglish (US)
Pages (from-to)714-718
Number of pages5
JournalClinical Microbiology and Infection
Volume17
Issue number5
DOIs
StatePublished - Jan 1 2011

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Integrons
Methicillin-Resistant Staphylococcus aureus
China
Microbial Drug Resistance
Genes

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Infectious Diseases

Cite this

Resistance class 1 integron in clinical methicillin-resistant Staphylococcus aureus strains in southern China, 2001-2006. / Xu, Z.; Li, L.; Shirtliff, M. E.; Peters, Brian; Li, B.; Peng, Y.; Alam, M. J.; Yamasaki, S.; Shi, L.

In: Clinical Microbiology and Infection, Vol. 17, No. 5, 01.01.2011, p. 714-718.

Research output: Contribution to journalArticle

Xu, Z. ; Li, L. ; Shirtliff, M. E. ; Peters, Brian ; Li, B. ; Peng, Y. ; Alam, M. J. ; Yamasaki, S. ; Shi, L. / Resistance class 1 integron in clinical methicillin-resistant Staphylococcus aureus strains in southern China, 2001-2006. In: Clinical Microbiology and Infection. 2011 ; Vol. 17, No. 5. pp. 714-718.
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