Resources for systems genetics

Robert Williams, Evan G. Williams

Research output: Chapter in Book/Report/Conference proceedingChapter

10 Citations (Scopus)

Abstract

A key characteristic of systems genetics is its reliance on populations that vary to a greater or lesser degree in genetic complexity—from highly admixed populations such as the Collaborative Cross and Diversity Outcross to relatively simple crosses such as sets of consomic strains and reduced complexity crosses. This protocol is intended to help investigators make more informed decisions about choices of resources given different types of questions. We consider factors such as costs, availability, and ease of breeding for common scenarios. In general, we recommend using complementary resources and minimizing depth of resampling of any given genome or strain.

Original languageEnglish (US)
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages1-29
Number of pages29
DOIs
StatePublished - Jan 1 2017

Publication series

NameMethods in Molecular Biology
Volume1488
ISSN (Print)1064-3745

Fingerprint

Population
Breeding
Research Personnel
Genome
Costs and Cost Analysis

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Genetics

Cite this

Williams, R., & Williams, E. G. (2017). Resources for systems genetics. In Methods in Molecular Biology (pp. 1-29). (Methods in Molecular Biology; Vol. 1488). Humana Press Inc.. https://doi.org/10.1007/978-1-4939-6427-7_1

Resources for systems genetics. / Williams, Robert; Williams, Evan G.

Methods in Molecular Biology. Humana Press Inc., 2017. p. 1-29 (Methods in Molecular Biology; Vol. 1488).

Research output: Chapter in Book/Report/Conference proceedingChapter

Williams, R & Williams, EG 2017, Resources for systems genetics. in Methods in Molecular Biology. Methods in Molecular Biology, vol. 1488, Humana Press Inc., pp. 1-29. https://doi.org/10.1007/978-1-4939-6427-7_1
Williams R, Williams EG. Resources for systems genetics. In Methods in Molecular Biology. Humana Press Inc. 2017. p. 1-29. (Methods in Molecular Biology). https://doi.org/10.1007/978-1-4939-6427-7_1
Williams, Robert ; Williams, Evan G. / Resources for systems genetics. Methods in Molecular Biology. Humana Press Inc., 2017. pp. 1-29 (Methods in Molecular Biology).
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