Reversible congestive heart failure related to profound hypocalcemia secondary to hypoparathyroidism

Asif S. Kazmi, Barry Wall

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

A 71-year-old man presented with acute pulmonary edema related to new onset of severe left ventricular dysfunction (ejection fraction, 30%). His symptoms did not improve with emergency therapy with diuretics and dobutamine. He was noted to be severely hypocalcemic (5.5 mg/dL) and subsequently showed dramatic improvement in symptoms and ejection fraction (58%) with correction of hypocalcemia with intravenous calcium and calcitriol replacement. Hypocalcemia was related to surgically induced hypoparathyroidism. The patient had been instructed to decrease calcium supplements and to discontinue calcitriol 3 months previously due to hypercalcemia. Additional factors that may have contributed to hypocalcemia included vitamin D deficiency, alendronate therapy for osteoporosis, and chronic kidney disease. We concluded that the patient's congestive heart failure was precipitated by severe hypocalcemia and resolved with correction of hypocalcemia. Hypocalcemia is a rare cause of reversible congestive heart failure that should be in the differential diagnosis in any patient presenting with heart failure and not responding to traditional therapy.

Original languageEnglish (US)
Pages (from-to)226-229
Number of pages4
JournalAmerican Journal of the Medical Sciences
Volume333
Issue number4
DOIs
StatePublished - Apr 1 2007

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Hypoparathyroidism
Hypocalcemia
Heart Failure
Calcitriol
Calcium
Alendronate
Vitamin D Deficiency
Dobutamine
Emergency Treatment
Hypercalcemia
Left Ventricular Dysfunction
Pulmonary Edema
Chronic Renal Insufficiency
Diuretics
Stroke Volume
Osteoporosis
Differential Diagnosis
Therapeutics

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Reversible congestive heart failure related to profound hypocalcemia secondary to hypoparathyroidism. / Kazmi, Asif S.; Wall, Barry.

In: American Journal of the Medical Sciences, Vol. 333, No. 4, 01.04.2007, p. 226-229.

Research output: Contribution to journalArticle

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