Risk factors for concomitant involvement of the female urethra at cystectomy for malignancy

H. Andrew Hollier, Howard B. Goldman, Anthony Patterson, Mitchell S. Steiner

Research output: Contribution to journalArticle

Abstract

To examine the risk factors for urethral involvement in female patients after cystectomy for malignancy, a retrospective review of the records of 22 females treated with cystectomy for primary bladder malignancy were examined and analyzed with respect to presence of urethral involvement, tumor location, pathologic stage, tumor grade, lymph node status, and histologic cell type of the cancer. Of the 22 patients studied, three (13.6%) had urethral involvement in the pathologic specimens. Bladder neck tumors represented a 33% risk of urethral involvement and trigonal tumors had a 20% associated risk. Higher pathologic stage corresponded with an increased risk because 18% of stage T3(b) and 33% of stage T4 patients had urethral involvement. Transitional cell carcinoma was the only histologic cell type to involve the urethra and represented a 17.6% risk. Any female patient undergoing cystectomy for bladder cancer with higher stage tumors (T3(b) and T4) involving the bladder neck and trigone should be considered as high risk for urethral involvement and should not be considered a candidate for orthotopic neobladder reconstruction.

Original languageEnglish (US)
Pages (from-to)189-191
Number of pages3
JournalUrologic Oncology
Volume3
Issue number5-6
DOIs
StatePublished - Sep 1 1997

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Cystectomy
Urethra
Neoplasms
Urinary Bladder Neoplasms
Urinary Bladder
Transitional Cell Carcinoma
Neck
Lymph Nodes

All Science Journal Classification (ASJC) codes

  • Oncology
  • Urology

Cite this

Risk factors for concomitant involvement of the female urethra at cystectomy for malignancy. / Hollier, H. Andrew; Goldman, Howard B.; Patterson, Anthony; Steiner, Mitchell S.

In: Urologic Oncology, Vol. 3, No. 5-6, 01.09.1997, p. 189-191.

Research output: Contribution to journalArticle

Hollier, H. Andrew ; Goldman, Howard B. ; Patterson, Anthony ; Steiner, Mitchell S. / Risk factors for concomitant involvement of the female urethra at cystectomy for malignancy. In: Urologic Oncology. 1997 ; Vol. 3, No. 5-6. pp. 189-191.
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