Role of transcranial Doppler ultrasonography in acute stroke

Vijay Sharma, N. Venketasubramanian, Dheeraj Khurana, Georgios Tsivgoulis, Andrei Alexandrov

Research output: Contribution to journalReview article

4 Citations (Scopus)

Abstract

Background: Transcranial Doppler (TCD) ultrasonography is the only noninvasive examination that provides a reliable evaluation of intracranial blood flow patterns in real-time, adding physiological information to the anatomical information obtained from other neuroimaging modalities. TCD is relatively cheap, can be performed bedside, and allows monitoring both in acute emergency settings as well as over prolonged periods; it has a high temporal resolution, making it ideal for studying dynamic cerebrovascular responses. Objective: To define the role of TCD in the evaluation of patients with acute ischemic stroke. Material and methods: We have analyzed the existing literature on the protocols for performing TCD in the evaluation of patients with acute cerebral ischemia. Extended applications of TCD in enhancing intravenous thrombolysis in acute stroke, emboli monitoring, right-to-left shunt detection, and vasomotor reactivity have also been described. Results: In acute cerebral ischemia, TCD is capable of providing rapid information about the hemodynamic status of the cerebral circulation, monitoring recanalization in real-time and, additionally, has a potential for enhancing tissue plasminogen activator (TPA)-induced thrombolysis. Extended applications of TCD make it an important and valuable tool for evaluating stroke mechanisms, for planning and monitoring treatment, and for determining prognosis. Discussion and conclusion: TCD has an established clinical value in the diagnostic workup of stroke patients and is suggested as one of the essential components of a comprehensive stroke center. TCD is also an evolving ultrasound method with increasing diagnostic value and a therapeutic potential in cerebral ischemia.

Original languageEnglish (US)
JournalAnnals of Indian Academy of Neurology
Volume11
Issue numberSUPPL. 5
StatePublished - Jan 1 2008

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Doppler Transcranial Ultrasonography
Stroke
Brain Ischemia
Cerebrovascular Circulation
Tissue Plasminogen Activator
Embolism
Neuroimaging
Emergencies
Hemodynamics
Therapeutics

All Science Journal Classification (ASJC) codes

  • Clinical Neurology

Cite this

Role of transcranial Doppler ultrasonography in acute stroke. / Sharma, Vijay; Venketasubramanian, N.; Khurana, Dheeraj; Tsivgoulis, Georgios; Alexandrov, Andrei.

In: Annals of Indian Academy of Neurology, Vol. 11, No. SUPPL. 5, 01.01.2008.

Research output: Contribution to journalReview article

Sharma, Vijay ; Venketasubramanian, N. ; Khurana, Dheeraj ; Tsivgoulis, Georgios ; Alexandrov, Andrei. / Role of transcranial Doppler ultrasonography in acute stroke. In: Annals of Indian Academy of Neurology. 2008 ; Vol. 11, No. SUPPL. 5.
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