Schistosomiasis mansoni in low transmission areas. Abdominal ultrasound

R. Ruiz, P. Candia, M. Garassini, Claudio Tombazzi, G. Certad, A. C. Bruces, O. Noya, B. Alarcón De Noya

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

In endemic areas with low prevalence and low intensity of infection, the diagnosis of hepatic pathology due to the Schistosoma mansoni infection is very difficult. In order to establish the hepatic morbidity, a double-blind study was achieved in Venezuelan endemic areas, with one group of patients with schistosomiasis and the other one of non-infected people, that were evaluated clinically and by abdominal ultrasound using the Cairo classification. Schistosomiasis diagnosis was established based on parasitologic and serological tests. The increase of the hepatic size at midclavicular and midsternal lines (in hepatometry) and the hard liver consistency were the clinical parameters able to differentiate infected persons from non infected ones, as well as the presence of left lobe hepatomegaly detected by abdominal ultrasound. The periportal thickening, especially the mild form, was frequent in all age groups in both infected and uninfected patients. There was not correlation between the intensity of infection and ultrasound under the current circumstances. Our data suggest that in Venezuela, a low endemic area of transmission of schistosomiasis, the hepatic morbidity is mild and uncommon. The Cairo classification seems to overestimate the prevalence of periportal pathology. The specificity of the method must be improved, especially for the recognition of precocious pathology. Other causes of hepatopathies must be investigated.

Original languageEnglish (US)
Pages (from-to)153-159
Number of pages7
JournalMemorias do Instituto Oswaldo Cruz
Volume97
Issue numberSUPPL. 1
DOIs
StatePublished - Jan 1 2002
Externally publishedYes

Fingerprint

Schistosomiasis mansoni
Schistosomiasis
Liver
Pathology
Morbidity
Venezuela
Hepatomegaly
Serologic Tests
Infection
Double-Blind Method
Age Groups

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)

Cite this

Ruiz, R., Candia, P., Garassini, M., Tombazzi, C., Certad, G., Bruces, A. C., ... Alarcón De Noya, B. (2002). Schistosomiasis mansoni in low transmission areas. Abdominal ultrasound. Memorias do Instituto Oswaldo Cruz, 97(SUPPL. 1), 153-159. https://doi.org/10.1590/S0074-02762002000900029

Schistosomiasis mansoni in low transmission areas. Abdominal ultrasound. / Ruiz, R.; Candia, P.; Garassini, M.; Tombazzi, Claudio; Certad, G.; Bruces, A. C.; Noya, O.; Alarcón De Noya, B.

In: Memorias do Instituto Oswaldo Cruz, Vol. 97, No. SUPPL. 1, 01.01.2002, p. 153-159.

Research output: Contribution to journalArticle

Ruiz, R, Candia, P, Garassini, M, Tombazzi, C, Certad, G, Bruces, AC, Noya, O & Alarcón De Noya, B 2002, 'Schistosomiasis mansoni in low transmission areas. Abdominal ultrasound', Memorias do Instituto Oswaldo Cruz, vol. 97, no. SUPPL. 1, pp. 153-159. https://doi.org/10.1590/S0074-02762002000900029
Ruiz, R. ; Candia, P. ; Garassini, M. ; Tombazzi, Claudio ; Certad, G. ; Bruces, A. C. ; Noya, O. ; Alarcón De Noya, B. / Schistosomiasis mansoni in low transmission areas. Abdominal ultrasound. In: Memorias do Instituto Oswaldo Cruz. 2002 ; Vol. 97, No. SUPPL. 1. pp. 153-159.
@article{cbba7d78d0b5496e8fe24fea8da9f4e3,
title = "Schistosomiasis mansoni in low transmission areas. Abdominal ultrasound",
abstract = "In endemic areas with low prevalence and low intensity of infection, the diagnosis of hepatic pathology due to the Schistosoma mansoni infection is very difficult. In order to establish the hepatic morbidity, a double-blind study was achieved in Venezuelan endemic areas, with one group of patients with schistosomiasis and the other one of non-infected people, that were evaluated clinically and by abdominal ultrasound using the Cairo classification. Schistosomiasis diagnosis was established based on parasitologic and serological tests. The increase of the hepatic size at midclavicular and midsternal lines (in hepatometry) and the hard liver consistency were the clinical parameters able to differentiate infected persons from non infected ones, as well as the presence of left lobe hepatomegaly detected by abdominal ultrasound. The periportal thickening, especially the mild form, was frequent in all age groups in both infected and uninfected patients. There was not correlation between the intensity of infection and ultrasound under the current circumstances. Our data suggest that in Venezuela, a low endemic area of transmission of schistosomiasis, the hepatic morbidity is mild and uncommon. The Cairo classification seems to overestimate the prevalence of periportal pathology. The specificity of the method must be improved, especially for the recognition of precocious pathology. Other causes of hepatopathies must be investigated.",
author = "R. Ruiz and P. Candia and M. Garassini and Claudio Tombazzi and G. Certad and Bruces, {A. C.} and O. Noya and {Alarc{\'o}n De Noya}, B.",
year = "2002",
month = "1",
day = "1",
doi = "10.1590/S0074-02762002000900029",
language = "English (US)",
volume = "97",
pages = "153--159",
journal = "Memorias do Instituto Oswaldo Cruz",
issn = "0074-0276",
publisher = "Fundacao Oswaldo Cruz",
number = "SUPPL. 1",

}

TY - JOUR

T1 - Schistosomiasis mansoni in low transmission areas. Abdominal ultrasound

AU - Ruiz, R.

AU - Candia, P.

AU - Garassini, M.

AU - Tombazzi, Claudio

AU - Certad, G.

AU - Bruces, A. C.

AU - Noya, O.

AU - Alarcón De Noya, B.

PY - 2002/1/1

Y1 - 2002/1/1

N2 - In endemic areas with low prevalence and low intensity of infection, the diagnosis of hepatic pathology due to the Schistosoma mansoni infection is very difficult. In order to establish the hepatic morbidity, a double-blind study was achieved in Venezuelan endemic areas, with one group of patients with schistosomiasis and the other one of non-infected people, that were evaluated clinically and by abdominal ultrasound using the Cairo classification. Schistosomiasis diagnosis was established based on parasitologic and serological tests. The increase of the hepatic size at midclavicular and midsternal lines (in hepatometry) and the hard liver consistency were the clinical parameters able to differentiate infected persons from non infected ones, as well as the presence of left lobe hepatomegaly detected by abdominal ultrasound. The periportal thickening, especially the mild form, was frequent in all age groups in both infected and uninfected patients. There was not correlation between the intensity of infection and ultrasound under the current circumstances. Our data suggest that in Venezuela, a low endemic area of transmission of schistosomiasis, the hepatic morbidity is mild and uncommon. The Cairo classification seems to overestimate the prevalence of periportal pathology. The specificity of the method must be improved, especially for the recognition of precocious pathology. Other causes of hepatopathies must be investigated.

AB - In endemic areas with low prevalence and low intensity of infection, the diagnosis of hepatic pathology due to the Schistosoma mansoni infection is very difficult. In order to establish the hepatic morbidity, a double-blind study was achieved in Venezuelan endemic areas, with one group of patients with schistosomiasis and the other one of non-infected people, that were evaluated clinically and by abdominal ultrasound using the Cairo classification. Schistosomiasis diagnosis was established based on parasitologic and serological tests. The increase of the hepatic size at midclavicular and midsternal lines (in hepatometry) and the hard liver consistency were the clinical parameters able to differentiate infected persons from non infected ones, as well as the presence of left lobe hepatomegaly detected by abdominal ultrasound. The periportal thickening, especially the mild form, was frequent in all age groups in both infected and uninfected patients. There was not correlation between the intensity of infection and ultrasound under the current circumstances. Our data suggest that in Venezuela, a low endemic area of transmission of schistosomiasis, the hepatic morbidity is mild and uncommon. The Cairo classification seems to overestimate the prevalence of periportal pathology. The specificity of the method must be improved, especially for the recognition of precocious pathology. Other causes of hepatopathies must be investigated.

UR - http://www.scopus.com/inward/record.url?scp=0036370419&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036370419&partnerID=8YFLogxK

U2 - 10.1590/S0074-02762002000900029

DO - 10.1590/S0074-02762002000900029

M3 - Article

VL - 97

SP - 153

EP - 159

JO - Memorias do Instituto Oswaldo Cruz

JF - Memorias do Instituto Oswaldo Cruz

SN - 0074-0276

IS - SUPPL. 1

ER -