Serology of Naegleria fowleri and Naegleria lovaniensis in a Hospital Survey

Barbara Dubray-Benstein, WALTER E. WILHELM, B. R. JENNINGS

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

An avidin‐biotin horseradish peroxidase method was used to detect antibodies to Naegleria fowleri and N. lovaniensis in human serum samples. Antibodies were detected in 101 specimens from 115 hospital patients ranging in age from 15 to 98 years. Class‐specific anti‐immunoglobulins identified antibodies as IgG and IgM. IgG antibody titers to both species ranged from 1:20 to 1:640. Seven of 15 serum samples collected from newborn infants also demonstrated IgG antibodies to these organisms with a titer range of 1:20 to 1:80. The immunoperoxidase test and Western blot analysis of selected serum samples demonstrated a close similarity in serological results between N. fowleri and N. lovaniensis.

Original languageEnglish (US)
Pages (from-to)322-327
Number of pages6
JournalThe Journal of Protozoology
Volume34
Issue number3
DOIs
StatePublished - Jan 1 1987
Externally publishedYes

Fingerprint

Naegleria fowleri
Naegleria
Serology
Antibodies
Immunoglobulin G
Serum
Horseradish Peroxidase
Immunoglobulin M
Western Blotting
Surveys and Questionnaires
Newborn Infant

All Science Journal Classification (ASJC) codes

  • Parasitology

Cite this

Serology of Naegleria fowleri and Naegleria lovaniensis in a Hospital Survey. / Dubray-Benstein, Barbara; WILHELM, WALTER E.; JENNINGS, B. R.

In: The Journal of Protozoology, Vol. 34, No. 3, 01.01.1987, p. 322-327.

Research output: Contribution to journalArticle

Dubray-Benstein, Barbara ; WILHELM, WALTER E. ; JENNINGS, B. R. / Serology of Naegleria fowleri and Naegleria lovaniensis in a Hospital Survey. In: The Journal of Protozoology. 1987 ; Vol. 34, No. 3. pp. 322-327.
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