Severe Multicore Disease Associated with Reaction to Anesthesia

Barbara M. Koch, Tulio Bertorini, Gloria D. Eng, Robert Boehm

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Multicore disease is a nonprogressive myopathy. To our knowledge, in all previous cases, the clinical course has been benign with no deaths attributed to it. We describe a patient who presented as a floppy baby and remained weaker throughout his life than any other patients previously described. Biopsy findings were characteristic of multicore disease. However, at age 21/2 years, our patient developed congestive heart failure that was easily controlled with digitalis and diuretics. Shortly after cardiac catheterization, the patient developed a high, unexplained fever and died 26 hours later despite aggressive attempts at resuscitation. Therefore, patients with multicores in skeletal muscle may have severe weakness and may also have a predisposition to complications subsequent to anesthesia.

Original languageEnglish (US)
Pages (from-to)1204-1206
Number of pages3
JournalArchives of Neurology
Volume42
Issue number12
DOIs
StatePublished - Jan 1 1985

Fingerprint

Anesthesia
Digitalis
Muscular Diseases
Cardiac Catheterization
Diuretics
Resuscitation
Skeletal Muscle
Fever
Heart Failure
Minicore Myopathy with External Ophthalmoplegia
Biopsy

All Science Journal Classification (ASJC) codes

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology

Cite this

Severe Multicore Disease Associated with Reaction to Anesthesia. / Koch, Barbara M.; Bertorini, Tulio; Eng, Gloria D.; Boehm, Robert.

In: Archives of Neurology, Vol. 42, No. 12, 01.01.1985, p. 1204-1206.

Research output: Contribution to journalArticle

Koch, Barbara M. ; Bertorini, Tulio ; Eng, Gloria D. ; Boehm, Robert. / Severe Multicore Disease Associated with Reaction to Anesthesia. In: Archives of Neurology. 1985 ; Vol. 42, No. 12. pp. 1204-1206.
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