Sex differences in ethanol-related behaviors in genetically defined murine stocks.

Byron Jones, K. E. Whitfield

Research output: Contribution to journalReview article

14 Citations (Scopus)

Abstract

Over the past 30 years, there have been a number of important developments in our understanding of the etiology and consequences of excessive drinking among humans. Probably one of the most important findings to date is that there are large individual differences among humans in appetite for alcohol and age of onset of problem drinking. We recognize this finding in at least two different alcoholic types, each with its own estimate of genetic influence. We have also come to realize that there are important differences between men and women, both in etiology of problem drinking and in the consequences of chronic alcohol use. In this chapter, the advantages and limitations of applying genetically defined animal models, primarily, selected lines and inbred strains of mice, are evaluated with examples from the literature.

Original languageEnglish (US)
Pages (from-to)223-230
Number of pages8
JournalRecent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism
Volume12
StatePublished - 1995
Externally publishedYes

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Sex Characteristics
Drinking
Ethanol
Alcohols
Inbred Strains Mice
Appetite
Age of Onset
Individuality
Animal Models

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

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abstract = "Over the past 30 years, there have been a number of important developments in our understanding of the etiology and consequences of excessive drinking among humans. Probably one of the most important findings to date is that there are large individual differences among humans in appetite for alcohol and age of onset of problem drinking. We recognize this finding in at least two different alcoholic types, each with its own estimate of genetic influence. We have also come to realize that there are important differences between men and women, both in etiology of problem drinking and in the consequences of chronic alcohol use. In this chapter, the advantages and limitations of applying genetically defined animal models, primarily, selected lines and inbred strains of mice, are evaluated with examples from the literature.",
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JO - Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism

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