Simulation and validation of point spread functions in pinhole imaging

Tobias Funk, Dennis L. Kirch, Mingshan Sun, Enrique Izaguirre, John E. Koss, Bruce H. Hasegawa

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

Modeling and assessment of point spread functions (PSF) of pinhole collimators is essential for the design of small animal SPECT imaging systems. PSFs also can be used in resolution recovery methods implemented into reconstruction algorithms. Therefore, we have developed and validated a ray tracing approach to simulate PSFs. The PSFs were calculated for user defined pinhole and source geometries with multiple rays to account for collimator penetration. For validation we compared our simulations to analytical models, Monte Carlo simulations from literature, and experiments with 99mTc sources using a variety of pinhole geometries including knife and keel edges. We find that shape and magnitude of the simulated PSFs are in very good agreement with analytical and experimental results. In particular, we find that the detection efficiency of a keel-edge pinhole decreases significantly faster with angle away from the central ray than for a knife-edge pinhole. The simulated projection data for a 99mTc-flood source demonstrated a detection efficiency of about 30% higher than its measured value; however, an overestimation of the detection efficiency is expected since our simulation omits scatter and attenuation in the object. In conclusion, we developed a simulation program which calculates the PSFs and detection efficiencies for different pinhole and source geometries fast and reliably.

Original languageEnglish (US)
Title of host publication2005 IEEE Nuclear Science Symposium Conference Record -Nuclear Science Symposium and Medical Imaging Conference
Pages2658-2663
Number of pages6
Volume5
DOIs
StatePublished - Dec 1 2005
Externally publishedYes
EventNuclear Science Symposium Conference Record, 2005 IEEE - , Puerto Rico
Duration: Oct 23 2005Oct 29 2005

Other

OtherNuclear Science Symposium Conference Record, 2005 IEEE
CountryPuerto Rico
Period10/23/0510/29/05

Fingerprint

Optical transfer function
Imaging techniques
Geometry
Ray tracing
Imaging systems
Analytical models
Animals
Recovery
Experiments

All Science Journal Classification (ASJC) codes

  • Computer Vision and Pattern Recognition
  • Industrial and Manufacturing Engineering

Cite this

Funk, T., Kirch, D. L., Sun, M., Izaguirre, E., Koss, J. E., & Hasegawa, B. H. (2005). Simulation and validation of point spread functions in pinhole imaging. In 2005 IEEE Nuclear Science Symposium Conference Record -Nuclear Science Symposium and Medical Imaging Conference (Vol. 5, pp. 2658-2663). [1596884] https://doi.org/10.1109/NSSMIC.2005.1596884

Simulation and validation of point spread functions in pinhole imaging. / Funk, Tobias; Kirch, Dennis L.; Sun, Mingshan; Izaguirre, Enrique; Koss, John E.; Hasegawa, Bruce H.

2005 IEEE Nuclear Science Symposium Conference Record -Nuclear Science Symposium and Medical Imaging Conference. Vol. 5 2005. p. 2658-2663 1596884.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Funk, T, Kirch, DL, Sun, M, Izaguirre, E, Koss, JE & Hasegawa, BH 2005, Simulation and validation of point spread functions in pinhole imaging. in 2005 IEEE Nuclear Science Symposium Conference Record -Nuclear Science Symposium and Medical Imaging Conference. vol. 5, 1596884, pp. 2658-2663, Nuclear Science Symposium Conference Record, 2005 IEEE, Puerto Rico, 10/23/05. https://doi.org/10.1109/NSSMIC.2005.1596884
Funk T, Kirch DL, Sun M, Izaguirre E, Koss JE, Hasegawa BH. Simulation and validation of point spread functions in pinhole imaging. In 2005 IEEE Nuclear Science Symposium Conference Record -Nuclear Science Symposium and Medical Imaging Conference. Vol. 5. 2005. p. 2658-2663. 1596884 https://doi.org/10.1109/NSSMIC.2005.1596884
Funk, Tobias ; Kirch, Dennis L. ; Sun, Mingshan ; Izaguirre, Enrique ; Koss, John E. ; Hasegawa, Bruce H. / Simulation and validation of point spread functions in pinhole imaging. 2005 IEEE Nuclear Science Symposium Conference Record -Nuclear Science Symposium and Medical Imaging Conference. Vol. 5 2005. pp. 2658-2663
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