Single daily dosing of methyldopa

M. E. Pipkin, P. E. Johnston, S. T. Miller, T. H. Self

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Thirteen adult hypertensive patients treated with multiple daily doses of methyldopa were studied to evaluate the efficacy and incidence of adverse reactions when converted to single daily (bedtime) doses of methyldopa. Patients were followed on their present regimen for 12 weeks, converted to bedtime dosing, and followed for the same period of time. Blood pressure measurements were taken at two-week intervals. Adverse effects, physical observations, laboratory data, and compliance were also evaluated at each visit. Blood pressure measurements showed little difference between the two regimens and adverse effects decreased on the bedtime schedule. Thus, single daily doses of methyldopa were shown to be safe and effective in the treatment of mild and moderate essential hypertension in these patients.

Original languageEnglish (US)
Pages (from-to)335-339
Number of pages5
JournalCurrent Therapeutic Research - Clinical and Experimental
Volume28
Issue number3 I
StatePublished - Jan 1 1980

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Methyldopa
Blood Pressure
Compliance
Appointments and Schedules
Incidence
Therapeutics

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmacology (medical)

Cite this

Pipkin, M. E., Johnston, P. E., Miller, S. T., & Self, T. H. (1980). Single daily dosing of methyldopa. Current Therapeutic Research - Clinical and Experimental, 28(3 I), 335-339.

Single daily dosing of methyldopa. / Pipkin, M. E.; Johnston, P. E.; Miller, S. T.; Self, T. H.

In: Current Therapeutic Research - Clinical and Experimental, Vol. 28, No. 3 I, 01.01.1980, p. 335-339.

Research output: Contribution to journalArticle

Pipkin, ME, Johnston, PE, Miller, ST & Self, TH 1980, 'Single daily dosing of methyldopa', Current Therapeutic Research - Clinical and Experimental, vol. 28, no. 3 I, pp. 335-339.
Pipkin ME, Johnston PE, Miller ST, Self TH. Single daily dosing of methyldopa. Current Therapeutic Research - Clinical and Experimental. 1980 Jan 1;28(3 I):335-339.
Pipkin, M. E. ; Johnston, P. E. ; Miller, S. T. ; Self, T. H. / Single daily dosing of methyldopa. In: Current Therapeutic Research - Clinical and Experimental. 1980 ; Vol. 28, No. 3 I. pp. 335-339.
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