Single-trial magnetoencephalography signals encoded as an unfolding decision process

Nikolaos Smyrnis, Dimitris S. Mylonas, Roozbeh Rezaie, Constantinos I. Siettos, Errikos Ventouras, Periklis Y. Ktonas, Ioannis Evdokimidis, Andrew Papanicolaou

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The model of a stochastic decision process unfolding in motor and premotor regions of the brain was encoded in single-trial magnetoencephalographic (MEG) recordings while ten healthy subjects performed a sensorimotor Reaction Time (RT) task. The duration of single-trial MEG signals preceding the motor response, recorded over the motor cortex contralateral to the responding hand, co-varied with RT across trials according to the model's prediction. Furthermore, these signals displayed the same properties of a "rising-to-a-fixed-threshold" decision process as posited by the model and observed in the activity of single neurons in the primate cortex. The present findings demonstrate that non-averaged, single-trial MEG recordings can be used to test models of cognitive processes, like decision-making, in humans.

Original languageEnglish (US)
Pages (from-to)3604-3610
Number of pages7
JournalNeuroImage
Volume59
Issue number4
DOIs
StatePublished - Feb 15 2012

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Stochastic Processes
Magnetoencephalography
Motor Cortex
Primates
Decision Making
Healthy Volunteers
Hand
Neurons
Brain

All Science Journal Classification (ASJC) codes

  • Neurology
  • Cognitive Neuroscience

Cite this

Smyrnis, N., Mylonas, D. S., Rezaie, R., Siettos, C. I., Ventouras, E., Ktonas, P. Y., ... Papanicolaou, A. (2012). Single-trial magnetoencephalography signals encoded as an unfolding decision process. NeuroImage, 59(4), 3604-3610. https://doi.org/10.1016/j.neuroimage.2011.10.091

Single-trial magnetoencephalography signals encoded as an unfolding decision process. / Smyrnis, Nikolaos; Mylonas, Dimitris S.; Rezaie, Roozbeh; Siettos, Constantinos I.; Ventouras, Errikos; Ktonas, Periklis Y.; Evdokimidis, Ioannis; Papanicolaou, Andrew.

In: NeuroImage, Vol. 59, No. 4, 15.02.2012, p. 3604-3610.

Research output: Contribution to journalArticle

Smyrnis, N, Mylonas, DS, Rezaie, R, Siettos, CI, Ventouras, E, Ktonas, PY, Evdokimidis, I & Papanicolaou, A 2012, 'Single-trial magnetoencephalography signals encoded as an unfolding decision process', NeuroImage, vol. 59, no. 4, pp. 3604-3610. https://doi.org/10.1016/j.neuroimage.2011.10.091
Smyrnis, Nikolaos ; Mylonas, Dimitris S. ; Rezaie, Roozbeh ; Siettos, Constantinos I. ; Ventouras, Errikos ; Ktonas, Periklis Y. ; Evdokimidis, Ioannis ; Papanicolaou, Andrew. / Single-trial magnetoencephalography signals encoded as an unfolding decision process. In: NeuroImage. 2012 ; Vol. 59, No. 4. pp. 3604-3610.
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