SIOP-PODC adapted risk stratification and treatment guidelines

Recommendations for neuroblastoma in low- and middle-income settings

Nehal S. Parikh, Scott Howard, Guillermo Chantada, Trijn Israels, Mohammed Khattab, Patricia Alcasabas, Catherine G. Lam, Lawrence Faulkner, Julie R. Park, Wendy B. London, Katherine K. Matthay

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Neuroblastoma is the most common extracranial solid tumor in childhood in high-income countries (HIC), where consistent treatment approaches based on clinical and tumor biological risk stratification have steadily improved outcomes. However, in low- and middle- income countries (LMIC), suboptimal diagnosis, risk stratification, and treatment may occur due to limited resources and unavailable infrastructure. The clinical practice guidelines outlined in this manuscript are based on current published evidence and expert opinions. Standard risk stratification and treatment explicitly adapted to graduated resource settings can improve outcomes for children with neuroblastoma by reducing preventable toxic death and relapse.

Original languageEnglish (US)
Pages (from-to)1305-1316
Number of pages12
JournalPediatric Blood and Cancer
Volume62
Issue number8
DOIs
StatePublished - Aug 1 2015

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Neuroblastoma
Guidelines
Poisons
Expert Testimony
Practice Guidelines
Neoplasms
Therapeutics
Recurrence

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology

Cite this

SIOP-PODC adapted risk stratification and treatment guidelines : Recommendations for neuroblastoma in low- and middle-income settings. / Parikh, Nehal S.; Howard, Scott; Chantada, Guillermo; Israels, Trijn; Khattab, Mohammed; Alcasabas, Patricia; Lam, Catherine G.; Faulkner, Lawrence; Park, Julie R.; London, Wendy B.; Matthay, Katherine K.

In: Pediatric Blood and Cancer, Vol. 62, No. 8, 01.08.2015, p. 1305-1316.

Research output: Contribution to journalArticle

Parikh, NS, Howard, S, Chantada, G, Israels, T, Khattab, M, Alcasabas, P, Lam, CG, Faulkner, L, Park, JR, London, WB & Matthay, KK 2015, 'SIOP-PODC adapted risk stratification and treatment guidelines: Recommendations for neuroblastoma in low- and middle-income settings', Pediatric Blood and Cancer, vol. 62, no. 8, pp. 1305-1316. https://doi.org/10.1002/pbc.25501
Parikh, Nehal S. ; Howard, Scott ; Chantada, Guillermo ; Israels, Trijn ; Khattab, Mohammed ; Alcasabas, Patricia ; Lam, Catherine G. ; Faulkner, Lawrence ; Park, Julie R. ; London, Wendy B. ; Matthay, Katherine K. / SIOP-PODC adapted risk stratification and treatment guidelines : Recommendations for neuroblastoma in low- and middle-income settings. In: Pediatric Blood and Cancer. 2015 ; Vol. 62, No. 8. pp. 1305-1316.
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