Skin Cancer Early Detection Practices among Adult Survivors of Childhood Cancer Treated with Radiation

Alan C. Geller, Robyn R. Keske, Sebastien Haneuse, Jessica A. Davine, Karen M. Emmons, Casey L. Daniel, Todd M. Gibson, Ashfaq Marghoob, Ann C. Mertens, Aaron J. McDonald, Leslie L. Robison, Rebecca M. Howell, John A. Whitton, Adina Coroiu, Wendy M. Leisenring, Gregory Armstrong

Research output: Contribution to journalArticle

Abstract

Because rates of skin cancer are greater among adult survivors of childhood cancer who received radiation therapy than among the general population, the National Cancer Institute recommends skin self-examinations and annual physician examination. There has been no comprehensive assessment of survivors’ adherence to the skin cancer screening guidelines associated with skin self-examination (SSE) and physician whole-body skin examination (PSE). We conducted a cross-sectional survey of radiation-treated, adult 5-year survivors of childhood cancer, diagnosed between 1970 and 1986, in the Childhood Cancer Survivor Study cohort. Multivariate multinomial logit regression investigated the association between demographic, cancer diagnosis, patient activation, cancer treatment characteristics, and skin cancer screening practice. Among 728 survivors, 13.1% reported performing SSE in the prior 2 months plus receiving PSE in the prior 12 months, and 16.4% and 11.0% reported performing only an SSE or a PSE, respectively; 59.5% of survivors reported having had neither. Participants at the highest patient activation score were most likely to report SSE plus PSE compared with neither (adjusted relative risk ratio = 4.16, 95% confidence interval = 1.34–12.85). Most adult survivors of childhood cancer who had radiation therapy do not practice strategies that promote early detection of skin cancer. Interventions designed to activate survivors to increase their participation in screening are needed.

Original languageEnglish (US)
Pages (from-to)1898-1905.e2
JournalJournal of Investigative Dermatology
Volume139
Issue number9
DOIs
StatePublished - Sep 1 2019

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Skin Neoplasms
Self-Examination
Survivors
Skin
Radiation
Neoplasms
Early Detection of Cancer
Patient Participation
Screening
Radiotherapy
Physicians
Chemical activation
National Cancer Institute (U.S.)
Oncology
Cohort Studies
Cross-Sectional Studies
Odds Ratio
Demography
Guidelines
Confidence Intervals

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology
  • Dermatology
  • Cell Biology

Cite this

Skin Cancer Early Detection Practices among Adult Survivors of Childhood Cancer Treated with Radiation. / Geller, Alan C.; Keske, Robyn R.; Haneuse, Sebastien; Davine, Jessica A.; Emmons, Karen M.; Daniel, Casey L.; Gibson, Todd M.; Marghoob, Ashfaq; Mertens, Ann C.; McDonald, Aaron J.; Robison, Leslie L.; Howell, Rebecca M.; Whitton, John A.; Coroiu, Adina; Leisenring, Wendy M.; Armstrong, Gregory.

In: Journal of Investigative Dermatology, Vol. 139, No. 9, 01.09.2019, p. 1898-1905.e2.

Research output: Contribution to journalArticle

Geller, AC, Keske, RR, Haneuse, S, Davine, JA, Emmons, KM, Daniel, CL, Gibson, TM, Marghoob, A, Mertens, AC, McDonald, AJ, Robison, LL, Howell, RM, Whitton, JA, Coroiu, A, Leisenring, WM & Armstrong, G 2019, 'Skin Cancer Early Detection Practices among Adult Survivors of Childhood Cancer Treated with Radiation', Journal of Investigative Dermatology, vol. 139, no. 9, pp. 1898-1905.e2. https://doi.org/10.1016/j.jid.2019.02.033
Geller, Alan C. ; Keske, Robyn R. ; Haneuse, Sebastien ; Davine, Jessica A. ; Emmons, Karen M. ; Daniel, Casey L. ; Gibson, Todd M. ; Marghoob, Ashfaq ; Mertens, Ann C. ; McDonald, Aaron J. ; Robison, Leslie L. ; Howell, Rebecca M. ; Whitton, John A. ; Coroiu, Adina ; Leisenring, Wendy M. ; Armstrong, Gregory. / Skin Cancer Early Detection Practices among Adult Survivors of Childhood Cancer Treated with Radiation. In: Journal of Investigative Dermatology. 2019 ; Vol. 139, No. 9. pp. 1898-1905.e2.
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