Sleep-awake responses elicited from medial preoptic area on application of norepinephrine and phenoxybenzamine in free moving rats

V. Mohan Kumar, Subimal Datta, G. S. Chihina, N. Gandhi, B. Singh

Research output: Contribution to journalArticle

54 Citations (Scopus)

Abstract

The study makes an attempt to find out the action of norepinephrine (NE) and phenoxybenzamine (PB), applied at medial preoptic area (mPOA), in altering the sleep-awake responses, in free moving rats, which has not yet been reported. Effects of application of NE during day and PB during night, at mPOA, on sleep-awake responses, were compared with application of saline during identical periods. Application of NE produced arousal, whereas, PB produced the opposite effect. The findings are suggestive of the involvement of NE terminals at mPOA in normal arousal.

Original languageEnglish (US)
Pages (from-to)322-325
Number of pages4
JournalBrain Research
Volume322
Issue number2
DOIs
StatePublished - Nov 26 1984
Externally publishedYes

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Phenoxybenzamine
Preoptic Area
Norepinephrine
Sleep
Arousal

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

Cite this

Sleep-awake responses elicited from medial preoptic area on application of norepinephrine and phenoxybenzamine in free moving rats. / Mohan Kumar, V.; Datta, Subimal; Chihina, G. S.; Gandhi, N.; Singh, B.

In: Brain Research, Vol. 322, No. 2, 26.11.1984, p. 322-325.

Research output: Contribution to journalArticle

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