Small-cell carcinoma of the cervix presenting with severe hypokalemia as a manifestation of cushing's syndrome

Mack N. Barnes, John E. Maxwell, Phillip Y. Roland, Larry Kilgore

Research output: Contribution to journalArticle

Abstract

Objectives. A case of small-cell carcinoma of the cervix and severe hypokalemia is presented. The need for surveillance of paraneoplastic syndromes in these patients is emphasized. Methods. The patient's clinical course is presented. The available literature regarding small-cell carcinoma of the cervix and Cushing's syndrome is reviewed. Results. A 32-year-old woman had diagnosed small-cell carcinoma after simple hysterectomy. After radical parametrectomy, she developed liver metastases that did not respond to chemotherapy. Subsequently, she developed severe and unremitting hypokalemia, which was determined to be the initial manifestation of Cushing's syndrome secondary to ectopic adenocorticotropic hormone production. Typical clinical features of Cushing's syndrome were noted to arise during subsequent examinations. Conclusions. Though paraneoplastic syndromes associated with small-cell carcinoma of the cervix are rare, this case report describes one of these syndromes as an etiology for metabolic derangements.

Original languageEnglish (US)
Pages (from-to)260-262
Number of pages3
JournalJournal of Lower Genital Tract Disease
Volume1
Issue number4
DOIs
StatePublished - Jan 1 1997

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Small Cell Carcinoma
Hypokalemia
Cushing Syndrome
Cervix Uteri
Paraneoplastic Syndromes
Ectopic Hormones
Hysterectomy
Neoplasm Metastasis
Drug Therapy
Liver

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynecology

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Small-cell carcinoma of the cervix presenting with severe hypokalemia as a manifestation of cushing's syndrome. / Barnes, Mack N.; Maxwell, John E.; Roland, Phillip Y.; Kilgore, Larry.

In: Journal of Lower Genital Tract Disease, Vol. 1, No. 4, 01.01.1997, p. 260-262.

Research output: Contribution to journalArticle

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