Socioeconomic impact of modern multidisciplinary management of retinoblastoma

Matthew Wilson, Barrett G. Haik, Carlos Rodriguez-Galindo

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

OBJECTIVE. Our objective for this study was to examine the impact of the modern management of intraocular retinoblastoma on the patient and the family. METHODS. This study comprises a retrospective, noncomparative case series of 25 consecutive patients with multifocal, intraocular retinoblastoma that was treated with primary systemic chemotherapy. Medical charts were reviewed, and the following data were extracted: patients' age and gender, laterality of disease, and Reese-Ellsworth classification of each eye as well as the number of central venous lines placed, cycles of chemotherapy received, outpatient appointments, examinations under anesthesia, focal therapies administered, computed tomography/MRI, radiation treatments, anesthetic procedures administered, and miles traveled. RESULTS. Twenty patients with bilateral and 5 with unilateral intraocular retinoblastoma (median age: 9.3 months) had 895 outpatient appointments and underwent 698 examinations under anesthesia with 230 focal therapies, 347 days of radiotherapy, 226 computed tomography scans/MRIs, and 38 central venous line placements. A total of 1272 anesthetic procedures (median: 50) were performed with no major complication. In all, patients traveled 822 312 miles (median: 22 214 miles) to receive their care. The median follow-up was 82 months. CONCLUSIONS. Successful retinoblastoma management requires close surveillance, aggressive consolidation, and numerous anesthetic procedures, all of which the patients and the families must endure. There is a significant impact on the patient, the family, and hospital resources.

Original languageEnglish (US)
JournalPediatrics
Volume118
Issue number2
DOIs
StatePublished - Aug 1 2006

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Retinoblastoma
Anesthetics
Appointments and Schedules
Outpatients
Anesthesia
Tomography
Drug Therapy
Radiotherapy
Therapeutics
Magnetic Resonance Imaging
Radiation

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health

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Socioeconomic impact of modern multidisciplinary management of retinoblastoma. / Wilson, Matthew; Haik, Barrett G.; Rodriguez-Galindo, Carlos.

In: Pediatrics, Vol. 118, No. 2, 01.08.2006.

Research output: Contribution to journalArticle

Wilson, Matthew ; Haik, Barrett G. ; Rodriguez-Galindo, Carlos. / Socioeconomic impact of modern multidisciplinary management of retinoblastoma. In: Pediatrics. 2006 ; Vol. 118, No. 2.
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