Somatostatin-14 and -28 in the male rat reproductive system

A. Eugene Pekary, Tadataka Yamada, Burt Sharp, Shalender Bhasin, Ronald S. Swerdloff, Jerome M. Hershman

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

Somatostatin-14 (SRIF-14) has been shown to occur throughout the male rat reproductive system by SRIF radioimmunoassay, Sephadex G-50 exclusion chromatography, and parallel line analysis. SRIF-28 was found only in the epididymis. The highest concentrations of total SRIF-like immunoreactivity (SLI), representing the combined concentrations of SRIF-14 and SRIF-28, were measured in the prostates of 1 1 2- and 3-month-old Sprague-Dawley rats. The lavels of SLI in prostates from 9-month-old males were about 10% that of the younger animals. Dilution curves for extracts of all reproductive tissues were parallel with synthetic SRIF-14.

Original languageEnglish (US)
Pages (from-to)939-945
Number of pages7
JournalLife Sciences
Volume34
Issue number10
DOIs
StatePublished - Mar 5 1984
Externally publishedYes

Fingerprint

Somatostatin-28
Somatostatin
Rats
Prostate
Epididymis
Chromatography
Dilution
Radioimmunoassay
Gel Chromatography
Sprague Dawley Rats
Animals
Tissue

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Eugene Pekary, A., Yamada, T., Sharp, B., Bhasin, S., Swerdloff, R. S., & Hershman, J. M. (1984). Somatostatin-14 and -28 in the male rat reproductive system. Life Sciences, 34(10), 939-945. https://doi.org/10.1016/0024-3205(84)90298-4

Somatostatin-14 and -28 in the male rat reproductive system. / Eugene Pekary, A.; Yamada, Tadataka; Sharp, Burt; Bhasin, Shalender; Swerdloff, Ronald S.; Hershman, Jerome M.

In: Life Sciences, Vol. 34, No. 10, 05.03.1984, p. 939-945.

Research output: Contribution to journalArticle

Eugene Pekary, A, Yamada, T, Sharp, B, Bhasin, S, Swerdloff, RS & Hershman, JM 1984, 'Somatostatin-14 and -28 in the male rat reproductive system', Life Sciences, vol. 34, no. 10, pp. 939-945. https://doi.org/10.1016/0024-3205(84)90298-4
Eugene Pekary A, Yamada T, Sharp B, Bhasin S, Swerdloff RS, Hershman JM. Somatostatin-14 and -28 in the male rat reproductive system. Life Sciences. 1984 Mar 5;34(10):939-945. https://doi.org/10.1016/0024-3205(84)90298-4
Eugene Pekary, A. ; Yamada, Tadataka ; Sharp, Burt ; Bhasin, Shalender ; Swerdloff, Ronald S. ; Hershman, Jerome M. / Somatostatin-14 and -28 in the male rat reproductive system. In: Life Sciences. 1984 ; Vol. 34, No. 10. pp. 939-945.
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