Splenium microstructure is related to two dimensions of reading skill

Richard E. Frye, Khader Hasan, Lian Xue, David Strickland, Benjamin Malmberg, Jacqueline Liederman, Andrew Papanicolaou

Research output: Contribution to journalArticle

56 Citations (Scopus)

Abstract

Inconsistent differences in the corpus callosum (CC) structure between dyslexic readers (DRs) and typical readers (TRs) have been reported. We examine differences in CC splenium microstructure and the association of splenium microstructure with reading-related skills. Nine DRs and 18 TRs completed a reading skills battery and diffusion tensor imaging. DRs had higher splenium fractional anisotropy (FA) and axial diffusivity (LA) as compared with TRs. Retrieval of orthographic information from the language lexicon was negatively associated with FA and LA within both reading groups. Phonological awareness was positively associated with splenium FA and LA in TRs but not DRs. This study suggests two white matter pathways that may be differentially associated with reading skills in the CC splenium.

Original languageEnglish (US)
Pages (from-to)1627-1631
Number of pages5
JournalNeuroReport
Volume19
Issue number16
DOIs
StatePublished - Oct 29 2008

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Corpus Callosum
Reading
Anisotropy
Diffusion Tensor Imaging
Information Storage and Retrieval
Language

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)

Cite this

Frye, R. E., Hasan, K., Xue, L., Strickland, D., Malmberg, B., Liederman, J., & Papanicolaou, A. (2008). Splenium microstructure is related to two dimensions of reading skill. NeuroReport, 19(16), 1627-1631. https://doi.org/10.1097/WNR.0b013e328314b8ee

Splenium microstructure is related to two dimensions of reading skill. / Frye, Richard E.; Hasan, Khader; Xue, Lian; Strickland, David; Malmberg, Benjamin; Liederman, Jacqueline; Papanicolaou, Andrew.

In: NeuroReport, Vol. 19, No. 16, 29.10.2008, p. 1627-1631.

Research output: Contribution to journalArticle

Frye, RE, Hasan, K, Xue, L, Strickland, D, Malmberg, B, Liederman, J & Papanicolaou, A 2008, 'Splenium microstructure is related to two dimensions of reading skill', NeuroReport, vol. 19, no. 16, pp. 1627-1631. https://doi.org/10.1097/WNR.0b013e328314b8ee
Frye RE, Hasan K, Xue L, Strickland D, Malmberg B, Liederman J et al. Splenium microstructure is related to two dimensions of reading skill. NeuroReport. 2008 Oct 29;19(16):1627-1631. https://doi.org/10.1097/WNR.0b013e328314b8ee
Frye, Richard E. ; Hasan, Khader ; Xue, Lian ; Strickland, David ; Malmberg, Benjamin ; Liederman, Jacqueline ; Papanicolaou, Andrew. / Splenium microstructure is related to two dimensions of reading skill. In: NeuroReport. 2008 ; Vol. 19, No. 16. pp. 1627-1631.
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