Squamous differentiation in a sarcomatoid chromophobe renal cell carcinoma

An unusual case report with review of the literature

Seethalakshmi Viswanathan, Sangeeta B. Desai, S. R. Prabhu, Mahul Amin

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

We describe an extremely rare occurrence of a squamous differentiation in a sarcomatoid chromophobe renal cell carcinoma in a 45-year-old woman with nodal and lung metastasis at presentation. The tumor on histology showed all 3 components intimately admixed with each other, which to the best of our knowledge is the first such case to be reported in the literature. The renal pelvis was smooth walled and uninvolved. Kidney-specific cadherin was positive in the chromophobe renal cell carcinoma areas and negative in the sarcomatoid and squamous areas.

Original languageEnglish (US)
Pages (from-to)1672-1674
Number of pages3
JournalArchives of Pathology and Laboratory Medicine
Volume132
Issue number10
StatePublished - Oct 2008
Externally publishedYes

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Renal Cell Carcinoma
Kidney Pelvis
Histology
Neoplasm Metastasis
Lung
Neoplasms

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology
  • Medicine(all)

Cite this

Squamous differentiation in a sarcomatoid chromophobe renal cell carcinoma : An unusual case report with review of the literature. / Viswanathan, Seethalakshmi; Desai, Sangeeta B.; Prabhu, S. R.; Amin, Mahul.

In: Archives of Pathology and Laboratory Medicine, Vol. 132, No. 10, 10.2008, p. 1672-1674.

Research output: Contribution to journalArticle

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