Structural remodeling of the myocardium postinfarction

Potential mechanisms and influence of therapy

Karl Weber, Yao Sun, J. P M Cleutjens

Research output: Contribution to journalReview article

5 Citations (Scopus)

Abstract

In patients who develop symptomatic heart failure after previous myocardial infarction, prognosis is poor and related to an activation of the circulating renin-angiotensin-aldosterone system. Emerging evidence would further implicate locally-generated peptide hormones in this process. Both circulating and tissue hormones contribute to an adverse structural remodeling of the myocardium and thereby influence the progressive nature of heart failure.

Original languageEnglish (US)
Pages (from-to)53-65
Number of pages13
JournalCardiology in Review
Volume3
Issue number1
DOIs
StatePublished - Mar 10 1995
Externally publishedYes

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Myocardium
Heart Failure
Peptide Hormones
Renin-Angiotensin System
Myocardial Infarction
Hormones
Therapeutics

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Structural remodeling of the myocardium postinfarction : Potential mechanisms and influence of therapy. / Weber, Karl; Sun, Yao; Cleutjens, J. P M.

In: Cardiology in Review, Vol. 3, No. 1, 10.03.1995, p. 53-65.

Research output: Contribution to journalReview article

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