Subclinical autonomic dysfunction in patients with beta-thalassemia

Elefterios Stamboulis, Nikoleta Vlachou, Konstantinos Voumvourakis, Athina Andrikopoulou, Chrisa Arvaniti, Athanasios Tsivgoulis, Dimitrios Athanasiadis, Sotirios Tsiodras, Nikolaos Tentolouris, Heleni Triantafyllidi, Marouso Drossou-Servou, Aphrodite Loutradi-Anagnostou, Georgios Tsivgoulis

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

We electrophysiologically evaluated the autonomic function (AF) in a consecutive series of patients with beta-thalassemia and in normal individuals. Six quantitative autonomic function tests (AFTs) were used: tilt test, hand grip test and sympathetic skin response for sympathetic function; R-R interval, inspiration-expiration difference and 30/15 ratio for parasympathetic function. The prevalence of impaired AF was higher in beta-thalassemia patients (13%, n = 5) than in control subjects (0%, n = 0; p = 0.026). Subclinical autonomic dysfunction appeared to be more prevalent in beta-thalassemia patients compared to controls in our series. Further independent validation of this finding is required in larger cohorts of beta-thalassemia patients.

Original languageEnglish (US)
Pages (from-to)147-150
Number of pages4
JournalClinical Autonomic Research
Volume22
Issue number3
DOIs
StatePublished - Jun 1 2012
Externally publishedYes

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beta-Thalassemia
Hand Strength
Skin Tests
Hand

All Science Journal Classification (ASJC) codes

  • Endocrine and Autonomic Systems
  • Clinical Neurology

Cite this

Stamboulis, E., Vlachou, N., Voumvourakis, K., Andrikopoulou, A., Arvaniti, C., Tsivgoulis, A., ... Tsivgoulis, G. (2012). Subclinical autonomic dysfunction in patients with beta-thalassemia. Clinical Autonomic Research, 22(3), 147-150. https://doi.org/10.1007/s10286-011-0154-2

Subclinical autonomic dysfunction in patients with beta-thalassemia. / Stamboulis, Elefterios; Vlachou, Nikoleta; Voumvourakis, Konstantinos; Andrikopoulou, Athina; Arvaniti, Chrisa; Tsivgoulis, Athanasios; Athanasiadis, Dimitrios; Tsiodras, Sotirios; Tentolouris, Nikolaos; Triantafyllidi, Heleni; Drossou-Servou, Marouso; Loutradi-Anagnostou, Aphrodite; Tsivgoulis, Georgios.

In: Clinical Autonomic Research, Vol. 22, No. 3, 01.06.2012, p. 147-150.

Research output: Contribution to journalArticle

Stamboulis, E, Vlachou, N, Voumvourakis, K, Andrikopoulou, A, Arvaniti, C, Tsivgoulis, A, Athanasiadis, D, Tsiodras, S, Tentolouris, N, Triantafyllidi, H, Drossou-Servou, M, Loutradi-Anagnostou, A & Tsivgoulis, G 2012, 'Subclinical autonomic dysfunction in patients with beta-thalassemia', Clinical Autonomic Research, vol. 22, no. 3, pp. 147-150. https://doi.org/10.1007/s10286-011-0154-2
Stamboulis E, Vlachou N, Voumvourakis K, Andrikopoulou A, Arvaniti C, Tsivgoulis A et al. Subclinical autonomic dysfunction in patients with beta-thalassemia. Clinical Autonomic Research. 2012 Jun 1;22(3):147-150. https://doi.org/10.1007/s10286-011-0154-2
Stamboulis, Elefterios ; Vlachou, Nikoleta ; Voumvourakis, Konstantinos ; Andrikopoulou, Athina ; Arvaniti, Chrisa ; Tsivgoulis, Athanasios ; Athanasiadis, Dimitrios ; Tsiodras, Sotirios ; Tentolouris, Nikolaos ; Triantafyllidi, Heleni ; Drossou-Servou, Marouso ; Loutradi-Anagnostou, Aphrodite ; Tsivgoulis, Georgios. / Subclinical autonomic dysfunction in patients with beta-thalassemia. In: Clinical Autonomic Research. 2012 ; Vol. 22, No. 3. pp. 147-150.
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