Subjective and objective analysis of the prevalence of Peyronie's disease in a population of men presenting for prostate cancer screening

John P. Mulhall, Steven D. Creech, Stephen A. Boorjian, Sam Ghaly, Edward Kim, Ayham Moty, Rodney Davis, Wayne Hellstrom

Research output: Contribution to journalArticle

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Abstract

Purpose: In this study we defined the prevalence of Peyronie's disease in a cohort of men being screened for prostate cancer in the United States. The association between Peyronie's disease, and medical comorbidities and patient self-reported erectile dysfunction was also defined. Materials and Methods: A total of 534 men presenting to 1 of 3 prostate cancer screening centers provided a complete medical history, underwent physical examination performed in all by a urologist and completed the Sexual Health Inventory for Men (SHIM) questionnaire. This population was chosen because of the access to a large number of subjects combined with the fact that subjects were not presenting with a specific urological complaint. The diagnosis of Peyronie's disease was based on a palpable penile plaque. Data were assessed using univariate analysis, multivariate logistic regression and Pearson chi-square analysis. Results: A total of 48 patients were found to have a palpable penile plaque on physical examination for a prevalence rate of 8.9%. The mean age of men with Peyronie's disease was 68.2 years compared to a mean of 61.8 years in men without Peyronie's disease (p < 0.0001). On univariate analysis hypertension (p = 0.02) and diabetes (p = 0.007) were present with significantly increased frequency in patients with Peyronie's disease. Patients diagnosed with Peyronie's disease had significantly lower values for responses to each of the 5 questions on the SHIM survey. An increase in age and decrease in total SHIM score remained significantly associated with a greater probability of Peyronie's disease on multivariate analysis. Conclusions: We found the prevalence of Peyronie's disease to be greater than in most previously reported series. We also noted a significant association between Peyronie's disease aging, hypertension, diabetes and self-reported erectile dysfunction.

Original languageEnglish (US)
Pages (from-to)2350-2353
Number of pages4
JournalJournal of Urology
Volume171
Issue number6 I
DOIs
StatePublished - Jan 1 2004
Externally publishedYes

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Penile Induration
Early Detection of Cancer
Prostatic Neoplasms
Population
Reproductive Health
Erectile Dysfunction
Equipment and Supplies
Physical Examination
Multivariate Analysis
Hypertension
Comorbidity
Cross-Sectional Studies
Logistic Models

All Science Journal Classification (ASJC) codes

  • Urology

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Subjective and objective analysis of the prevalence of Peyronie's disease in a population of men presenting for prostate cancer screening. / Mulhall, John P.; Creech, Steven D.; Boorjian, Stephen A.; Ghaly, Sam; Kim, Edward; Moty, Ayham; Davis, Rodney; Hellstrom, Wayne.

In: Journal of Urology, Vol. 171, No. 6 I, 01.01.2004, p. 2350-2353.

Research output: Contribution to journalArticle

Mulhall, John P. ; Creech, Steven D. ; Boorjian, Stephen A. ; Ghaly, Sam ; Kim, Edward ; Moty, Ayham ; Davis, Rodney ; Hellstrom, Wayne. / Subjective and objective analysis of the prevalence of Peyronie's disease in a population of men presenting for prostate cancer screening. In: Journal of Urology. 2004 ; Vol. 171, No. 6 I. pp. 2350-2353.
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T1 - Subjective and objective analysis of the prevalence of Peyronie's disease in a population of men presenting for prostate cancer screening

AU - Mulhall, John P.

AU - Creech, Steven D.

AU - Boorjian, Stephen A.

AU - Ghaly, Sam

AU - Kim, Edward

AU - Moty, Ayham

AU - Davis, Rodney

AU - Hellstrom, Wayne

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N2 - Purpose: In this study we defined the prevalence of Peyronie's disease in a cohort of men being screened for prostate cancer in the United States. The association between Peyronie's disease, and medical comorbidities and patient self-reported erectile dysfunction was also defined. Materials and Methods: A total of 534 men presenting to 1 of 3 prostate cancer screening centers provided a complete medical history, underwent physical examination performed in all by a urologist and completed the Sexual Health Inventory for Men (SHIM) questionnaire. This population was chosen because of the access to a large number of subjects combined with the fact that subjects were not presenting with a specific urological complaint. The diagnosis of Peyronie's disease was based on a palpable penile plaque. Data were assessed using univariate analysis, multivariate logistic regression and Pearson chi-square analysis. Results: A total of 48 patients were found to have a palpable penile plaque on physical examination for a prevalence rate of 8.9%. The mean age of men with Peyronie's disease was 68.2 years compared to a mean of 61.8 years in men without Peyronie's disease (p < 0.0001). On univariate analysis hypertension (p = 0.02) and diabetes (p = 0.007) were present with significantly increased frequency in patients with Peyronie's disease. Patients diagnosed with Peyronie's disease had significantly lower values for responses to each of the 5 questions on the SHIM survey. An increase in age and decrease in total SHIM score remained significantly associated with a greater probability of Peyronie's disease on multivariate analysis. Conclusions: We found the prevalence of Peyronie's disease to be greater than in most previously reported series. We also noted a significant association between Peyronie's disease aging, hypertension, diabetes and self-reported erectile dysfunction.

AB - Purpose: In this study we defined the prevalence of Peyronie's disease in a cohort of men being screened for prostate cancer in the United States. The association between Peyronie's disease, and medical comorbidities and patient self-reported erectile dysfunction was also defined. Materials and Methods: A total of 534 men presenting to 1 of 3 prostate cancer screening centers provided a complete medical history, underwent physical examination performed in all by a urologist and completed the Sexual Health Inventory for Men (SHIM) questionnaire. This population was chosen because of the access to a large number of subjects combined with the fact that subjects were not presenting with a specific urological complaint. The diagnosis of Peyronie's disease was based on a palpable penile plaque. Data were assessed using univariate analysis, multivariate logistic regression and Pearson chi-square analysis. Results: A total of 48 patients were found to have a palpable penile plaque on physical examination for a prevalence rate of 8.9%. The mean age of men with Peyronie's disease was 68.2 years compared to a mean of 61.8 years in men without Peyronie's disease (p < 0.0001). On univariate analysis hypertension (p = 0.02) and diabetes (p = 0.007) were present with significantly increased frequency in patients with Peyronie's disease. Patients diagnosed with Peyronie's disease had significantly lower values for responses to each of the 5 questions on the SHIM survey. An increase in age and decrease in total SHIM score remained significantly associated with a greater probability of Peyronie's disease on multivariate analysis. Conclusions: We found the prevalence of Peyronie's disease to be greater than in most previously reported series. We also noted a significant association between Peyronie's disease aging, hypertension, diabetes and self-reported erectile dysfunction.

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