Successful neurosurgical treatment of childhood complex partial status epilepticus with focal resection

Yu Tze Ng, Howard L. Kim, James Wheless

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

The treatment of complex partial status epilepticus continues to be controversial, especially with regard to the intensity of the treatment. Medical therapy and drug-induced coma are sometimes required. Rarely this may not be effective. A healthy 4-year old girl was first seen in complex partial status epilepticus. She had a 1-year history of cryptogenic partialonset seizures. Detailed magnetic resonance imaging (MRI) studies were normal, Her course was refractory to multiple medical therapies and multiple subpial transection (MST). An urgent epilepsy surgery evaluation resulted in a focal cortical resection being performed over the right mesial parietal region with resultant seizure freedom and no significant neurologic deficit 2 years later. This patient illustrates the need to consider occult focal cortical dysplasia as a cause of nonconvulsive status epilepticus (NCSE) in children, and if it is not responsive to medical management, the utility of performing an urgent epilepsy surgery evaluation.

Original languageEnglish (US)
Pages (from-to)468-471
Number of pages4
JournalEpilepsia
Volume44
Issue number3
DOIs
StatePublished - Mar 1 2003

Fingerprint

Status Epilepticus
Epilepsy
Seizures
Malformations of Cortical Development
Parietal Lobe
Coma
Neurologic Manifestations
Therapeutics
Magnetic Resonance Imaging
Drug Therapy

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology

Cite this

Successful neurosurgical treatment of childhood complex partial status epilepticus with focal resection. / Ng, Yu Tze; Kim, Howard L.; Wheless, James.

In: Epilepsia, Vol. 44, No. 3, 01.03.2003, p. 468-471.

Research output: Contribution to journalArticle

@article{7f7d77db438b44daa46db43efa5c2112,
title = "Successful neurosurgical treatment of childhood complex partial status epilepticus with focal resection",
abstract = "The treatment of complex partial status epilepticus continues to be controversial, especially with regard to the intensity of the treatment. Medical therapy and drug-induced coma are sometimes required. Rarely this may not be effective. A healthy 4-year old girl was first seen in complex partial status epilepticus. She had a 1-year history of cryptogenic partialonset seizures. Detailed magnetic resonance imaging (MRI) studies were normal, Her course was refractory to multiple medical therapies and multiple subpial transection (MST). An urgent epilepsy surgery evaluation resulted in a focal cortical resection being performed over the right mesial parietal region with resultant seizure freedom and no significant neurologic deficit 2 years later. This patient illustrates the need to consider occult focal cortical dysplasia as a cause of nonconvulsive status epilepticus (NCSE) in children, and if it is not responsive to medical management, the utility of performing an urgent epilepsy surgery evaluation.",
author = "Ng, {Yu Tze} and Kim, {Howard L.} and James Wheless",
year = "2003",
month = "3",
day = "1",
doi = "10.1046/j.1528-1157.2003.40302.x",
language = "English (US)",
volume = "44",
pages = "468--471",
journal = "Epilepsia",
issn = "0013-9580",
publisher = "Wiley-Blackwell",
number = "3",

}

TY - JOUR

T1 - Successful neurosurgical treatment of childhood complex partial status epilepticus with focal resection

AU - Ng, Yu Tze

AU - Kim, Howard L.

AU - Wheless, James

PY - 2003/3/1

Y1 - 2003/3/1

N2 - The treatment of complex partial status epilepticus continues to be controversial, especially with regard to the intensity of the treatment. Medical therapy and drug-induced coma are sometimes required. Rarely this may not be effective. A healthy 4-year old girl was first seen in complex partial status epilepticus. She had a 1-year history of cryptogenic partialonset seizures. Detailed magnetic resonance imaging (MRI) studies were normal, Her course was refractory to multiple medical therapies and multiple subpial transection (MST). An urgent epilepsy surgery evaluation resulted in a focal cortical resection being performed over the right mesial parietal region with resultant seizure freedom and no significant neurologic deficit 2 years later. This patient illustrates the need to consider occult focal cortical dysplasia as a cause of nonconvulsive status epilepticus (NCSE) in children, and if it is not responsive to medical management, the utility of performing an urgent epilepsy surgery evaluation.

AB - The treatment of complex partial status epilepticus continues to be controversial, especially with regard to the intensity of the treatment. Medical therapy and drug-induced coma are sometimes required. Rarely this may not be effective. A healthy 4-year old girl was first seen in complex partial status epilepticus. She had a 1-year history of cryptogenic partialonset seizures. Detailed magnetic resonance imaging (MRI) studies were normal, Her course was refractory to multiple medical therapies and multiple subpial transection (MST). An urgent epilepsy surgery evaluation resulted in a focal cortical resection being performed over the right mesial parietal region with resultant seizure freedom and no significant neurologic deficit 2 years later. This patient illustrates the need to consider occult focal cortical dysplasia as a cause of nonconvulsive status epilepticus (NCSE) in children, and if it is not responsive to medical management, the utility of performing an urgent epilepsy surgery evaluation.

UR - http://www.scopus.com/inward/record.url?scp=0037347253&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037347253&partnerID=8YFLogxK

U2 - 10.1046/j.1528-1157.2003.40302.x

DO - 10.1046/j.1528-1157.2003.40302.x

M3 - Article

C2 - 12614407

AN - SCOPUS:0037347253

VL - 44

SP - 468

EP - 471

JO - Epilepsia

JF - Epilepsia

SN - 0013-9580

IS - 3

ER -