Supportive medical care for children with acute lymphoblastic leukemia in low-and middle-income countries

Francesco Ceppi, Federico Antillon, Carlos Pacheco, Courtney E. Sullivan, Catherine G. Lam, Scott Howard, Valentino Conter

Research output: Contribution to journalReview article

4 Citations (Scopus)

Abstract

In the last two decades, remarkable progress in the treatment of children with acute lymphoblastic leukemia has been achieved in many low-and middle-income countries (LMIC), but survival rates remain significantly lower than those in high-income countries. Inadequate supportive care and consequent excess mortality from toxicity are important causes of treatment failure for children with acute lymphoblastic leukemia in LMIC. This article summarizes practical supportive care recommendations for healthcare providers practicing in LMIC, starting with core approaches in oncology nursing care, management of tumor lysis syndrome and mediastinal masses, nutritional support, use of blood products for anemia and thrombocytopenia, and palliative care. Prevention and treatment of infectious diseases are described in a parallel paper.

Original languageEnglish (US)
Pages (from-to)613-626
Number of pages14
JournalExpert Review of Hematology
Volume8
Issue number5
DOIs
StatePublished - Sep 3 2015

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Child Care
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Tumor Lysis Syndrome
Oncology Nursing
Nutritional Support
Nursing Care
Treatment Failure
Palliative Care
Thrombocytopenia
Health Personnel
Communicable Diseases
Anemia
Survival Rate
Mortality
Therapeutics

All Science Journal Classification (ASJC) codes

  • Hematology

Cite this

Supportive medical care for children with acute lymphoblastic leukemia in low-and middle-income countries. / Ceppi, Francesco; Antillon, Federico; Pacheco, Carlos; Sullivan, Courtney E.; Lam, Catherine G.; Howard, Scott; Conter, Valentino.

In: Expert Review of Hematology, Vol. 8, No. 5, 03.09.2015, p. 613-626.

Research output: Contribution to journalReview article

Ceppi, Francesco ; Antillon, Federico ; Pacheco, Carlos ; Sullivan, Courtney E. ; Lam, Catherine G. ; Howard, Scott ; Conter, Valentino. / Supportive medical care for children with acute lymphoblastic leukemia in low-and middle-income countries. In: Expert Review of Hematology. 2015 ; Vol. 8, No. 5. pp. 613-626.
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