Surgical and anesthetic management for hepatectomy in two pediatric patients with trisomy 18, pulmonary hypertension, and hepatoblastoma

Donald J. Lucas, Jeremy Rubinstein, Ankush Gosain, Greg Tiao, Tim Head, J. Nick Pratap, Regan Williams, Sara Helmig, James Geller, Max Langham, Angela Trobaugh-Lotrario

Research output: Contribution to journalArticle

Abstract

Children with trisomy 18 are surviving longer and undergoing more aggressive life-sustaining therapy. This report describes two patients with trisomy 18 and hepatoblastoma (HB) successfully resected in the setting of significant pulmonary hypertension. Forty-four previously published cases of the association between HB and trisomy 18 are reviewed. With careful multidisciplinary preoperative planning, successful resection of HB in children with trisomy 18 who have significant pulmonary hypertension is feasible. Because HB and trisomy 18 are increasing in prevalence, the need for timely liver tumor resection in the setting of pulmonary hypertension will be more common.

Original languageEnglish (US)
Article numbere27678
JournalPediatric Blood and Cancer
Volume66
Issue number6
DOIs
StatePublished - Jun 1 2019

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Hepatoblastoma
Hepatectomy
Pulmonary Hypertension
Anesthetics
Pediatrics
Trisomy 18
Liver
Neoplasms

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology

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Surgical and anesthetic management for hepatectomy in two pediatric patients with trisomy 18, pulmonary hypertension, and hepatoblastoma. / Lucas, Donald J.; Rubinstein, Jeremy; Gosain, Ankush; Tiao, Greg; Head, Tim; Pratap, J. Nick; Williams, Regan; Helmig, Sara; Geller, James; Langham, Max; Trobaugh-Lotrario, Angela.

In: Pediatric Blood and Cancer, Vol. 66, No. 6, e27678, 01.06.2019.

Research output: Contribution to journalArticle

Lucas, Donald J. ; Rubinstein, Jeremy ; Gosain, Ankush ; Tiao, Greg ; Head, Tim ; Pratap, J. Nick ; Williams, Regan ; Helmig, Sara ; Geller, James ; Langham, Max ; Trobaugh-Lotrario, Angela. / Surgical and anesthetic management for hepatectomy in two pediatric patients with trisomy 18, pulmonary hypertension, and hepatoblastoma. In: Pediatric Blood and Cancer. 2019 ; Vol. 66, No. 6.
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