Surgical biopsy prevented with PET/CT scan in a young female with intrathoracic lymphadenopathy.

Dipen Kadaria, Muthiah Muthiah, David S. Archie, Ibrahim Sultan-Ali, Muhammad K. Zaman

Research output: Contribution to journalArticle

Abstract

Intrathoracic lymphadenopathy is a common clinical problem encountered in Histoplasma endemic zones. It is challenging for clinicians to distinguish the infectious lesions from the neoplastic ones. Bronchoscopy with or without lung sampling and transbronchial needle aspiration (TBNA) is commonly the first diagnostic procedure employed. If non-diagnostic, the next step is usually surgical biopsy. In our experience, a significant number of patients who go for surgical biopsy are diagnosed with histoplasmosis. A positron emission tomography (PET) scan with dual-time imaging may help us distinguish benign from malignant lesions, thus obviating the need for surgical sampling. We report a case of a young female who presented with progressively increasing intrathoracic lymphadenopathy and was treated successfully based on dual-time PET scan results, without proceeding to surgical lung biopsy.

Original languageEnglish (US)
JournalTennessee medicine : journal of the Tennessee Medical Association
Volume105
Issue number10
StatePublished - Jan 1 2012

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Positron-Emission Tomography
Biopsy
Histoplasma
Histoplasmosis
Lung
Bronchoscopy
Needles
Lymphadenopathy

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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Surgical biopsy prevented with PET/CT scan in a young female with intrathoracic lymphadenopathy. / Kadaria, Dipen; Muthiah, Muthiah; Archie, David S.; Sultan-Ali, Ibrahim; Zaman, Muhammad K.

In: Tennessee medicine : journal of the Tennessee Medical Association, Vol. 105, No. 10, 01.01.2012.

Research output: Contribution to journalArticle

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