Symptomatic intradural adrenal adenoma of the spinal nerve root

Report of two cases

Andrew Mitchell, Bernd W. Scheithauer, Hironobu Sasano, Elizabeth Hubbard, Michael J. Ebersold

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

THE SECOND AND THIRD cases of an adrenal adenoma involving the intraspinal space, a rare location for a lesion that occurs rather commonly at a variety of extraneural sites, are reported. The first patient, a 16-year-old girl with a 3-month history of radicular pain, was found to have an intradural, extramedullary mass arising on a spinal nerve root. Its resection resulted in cure. The second patient, a 63-year-old woman with a 10-month history of low back pain with radiation to both lower extremities, had a similar mass arising from one of the nerve roots of the cauda equina. In both cases, ultrastructural examination of these demarcated, oncocytic, lipid-rich lesions demonstrated abundant smooth endoplasmic reticulum and mitochondria with tubular cristae. The presence of steroidogenic enzymes was noted on immunohistochemical examination. The literature is reviewed, as is the differential diagnosis of these rare lesions.

Original languageEnglish (US)
Pages (from-to)658-662
Number of pages5
JournalNeurosurgery
Volume32
Issue number4
DOIs
StatePublished - Jan 1 1993

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Spinal Nerve Roots
Adenoma
Cauda Equina
Smooth Endoplasmic Reticulum
Back Pain
Low Back Pain
Lower Extremity
Mitochondria
Differential Diagnosis
Lipids
Pain
Enzymes

All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology

Cite this

Symptomatic intradural adrenal adenoma of the spinal nerve root : Report of two cases. / Mitchell, Andrew; Scheithauer, Bernd W.; Sasano, Hironobu; Hubbard, Elizabeth; Ebersold, Michael J.

In: Neurosurgery, Vol. 32, No. 4, 01.01.1993, p. 658-662.

Research output: Contribution to journalArticle

Mitchell, Andrew ; Scheithauer, Bernd W. ; Sasano, Hironobu ; Hubbard, Elizabeth ; Ebersold, Michael J. / Symptomatic intradural adrenal adenoma of the spinal nerve root : Report of two cases. In: Neurosurgery. 1993 ; Vol. 32, No. 4. pp. 658-662.
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