Synthesis of biocompatible multicolor luminescent carbon dots for bioimaging applications

Nagaprasad Puvvada, Prashanth Kumar Bhusetty Nagesh, Suraj Konar, Himani Kalita, Mahitosh Mandal, Amita Pathak

Research output: Contribution to journalArticle

67 Citations (Scopus)

Abstract

Water-soluble carbon dots (C-dots) were prepared through microwave-assisted pyrolysis of an aqueous solution of dextrin in the presence of sulfuric acid. The C-dots produced showed multicolor luminescence in the entire visible range, without adding any surface-passivating agent. X-ray diffraction and Fourier transform infrared spectroscopy studies revealed the graphitic nature of the carbon and the presence of hydrophilic groups on the surface, respectively. The formation of uniformly distributed C-dots and their luminescent properties were, respectively, revealed from transmission electron microscopy and confocal laser scanning microscopy. The biocompatible nature of C-dots was confirmed by a cytotoxicity assay on MDA-MB-468 cells and their cellular uptake was assessed through a localization study.

Original languageEnglish (US)
Article number045008
JournalScience and Technology of Advanced Materials
Volume13
Issue number4
DOIs
StatePublished - Aug 1 2012

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Carbon
Cytotoxicity
Sulfuric acid
Fourier transform infrared spectroscopy
Luminescence
Assays
Microscopic examination
Pyrolysis
Microwaves
Transmission electron microscopy
Scanning
X ray diffraction
Water
Lasers

All Science Journal Classification (ASJC) codes

  • Materials Science(all)

Cite this

Synthesis of biocompatible multicolor luminescent carbon dots for bioimaging applications. / Puvvada, Nagaprasad; Bhusetty Nagesh, Prashanth Kumar; Konar, Suraj; Kalita, Himani; Mandal, Mahitosh; Pathak, Amita.

In: Science and Technology of Advanced Materials, Vol. 13, No. 4, 045008, 01.08.2012.

Research output: Contribution to journalArticle

Puvvada, Nagaprasad ; Bhusetty Nagesh, Prashanth Kumar ; Konar, Suraj ; Kalita, Himani ; Mandal, Mahitosh ; Pathak, Amita. / Synthesis of biocompatible multicolor luminescent carbon dots for bioimaging applications. In: Science and Technology of Advanced Materials. 2012 ; Vol. 13, No. 4.
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