Synthesis of nitrogen-13 labeled alkylamines via amination of organoboranes

Paresh J. Kothari, Ronald D. Finn, George Kabalka, Manhar M. Vora, Thomas E. Boothe, Ali M. Emran

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Organoboranes react with nitrogen-13 labeled ammonia to produce alkylamines in moderate yield. When 13N labeled ammonia was bubbled into a tetrahydrofuran solution containing 0.5M tridecylborane, 1-[13N]aminodecane was formed in 25-30 min from the end of bombardment (EOB) in 40-60% overall yield. 1-[13N]aminooctane and 1-[13N]aminohexane were also synthesized from appropriate organoboranes in similar yield.

Original languageEnglish (US)
Pages (from-to)469-470
Number of pages2
JournalInternational Journal of Radiation Applications and Instrumentation. Part
Volume37
Issue number6
DOIs
StatePublished - Jan 1 1986
Externally publishedYes

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Amination
Ammonia
Nitrogen
nitrogen
ammonia
synthesis
tetrahydrofuran
bombardment

All Science Journal Classification (ASJC) codes

  • Radiation
  • Engineering(all)

Cite this

Synthesis of nitrogen-13 labeled alkylamines via amination of organoboranes. / Kothari, Paresh J.; Finn, Ronald D.; Kabalka, George; Vora, Manhar M.; Boothe, Thomas E.; Emran, Ali M.

In: International Journal of Radiation Applications and Instrumentation. Part, Vol. 37, No. 6, 01.01.1986, p. 469-470.

Research output: Contribution to journalArticle

Kothari, Paresh J. ; Finn, Ronald D. ; Kabalka, George ; Vora, Manhar M. ; Boothe, Thomas E. ; Emran, Ali M. / Synthesis of nitrogen-13 labeled alkylamines via amination of organoboranes. In: International Journal of Radiation Applications and Instrumentation. Part. 1986 ; Vol. 37, No. 6. pp. 469-470.
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AU - Emran, Ali M.

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