Synthetic studies towards the identification of novel capuramycin analogs with mycobactericidal activity

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Expeditious syntheses of capuramycin, an effective MraY inhibitor in vivo, analogs are described. Synthetic schemes reported here are extremely useful for the generation of capuramycin analogs to identify minimum structure requirement to exhibit antimycobactericidal activity.

Original languageEnglish (US)
Pages (from-to)217-225
Number of pages9
JournalHeterocycles
Volume77
Issue number1
DOIs
StatePublished - Jan 1 2009
Externally publishedYes

Fingerprint

capuramycin

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

Cite this

Synthetic studies towards the identification of novel capuramycin analogs with mycobactericidal activity. / Kurosu, Michio; Li, Kai.

In: Heterocycles, Vol. 77, No. 1, 01.01.2009, p. 217-225.

Research output: Contribution to journalArticle

@article{7bb4018fe5a04a249de3c4969aa29d7c,
title = "Synthetic studies towards the identification of novel capuramycin analogs with mycobactericidal activity",
abstract = "Expeditious syntheses of capuramycin, an effective MraY inhibitor in vivo, analogs are described. Synthetic schemes reported here are extremely useful for the generation of capuramycin analogs to identify minimum structure requirement to exhibit antimycobactericidal activity.",
author = "Michio Kurosu and Kai Li",
year = "2009",
month = "1",
day = "1",
doi = "10.3987/COM-08-S(F)38",
language = "English (US)",
volume = "77",
pages = "217--225",
journal = "Heterocycles",
issn = "0385-5414",
publisher = "Japan Institute of Heterocyclic Chemistry",
number = "1",

}

TY - JOUR

T1 - Synthetic studies towards the identification of novel capuramycin analogs with mycobactericidal activity

AU - Kurosu, Michio

AU - Li, Kai

PY - 2009/1/1

Y1 - 2009/1/1

N2 - Expeditious syntheses of capuramycin, an effective MraY inhibitor in vivo, analogs are described. Synthetic schemes reported here are extremely useful for the generation of capuramycin analogs to identify minimum structure requirement to exhibit antimycobactericidal activity.

AB - Expeditious syntheses of capuramycin, an effective MraY inhibitor in vivo, analogs are described. Synthetic schemes reported here are extremely useful for the generation of capuramycin analogs to identify minimum structure requirement to exhibit antimycobactericidal activity.

UR - http://www.scopus.com/inward/record.url?scp=65549139464&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=65549139464&partnerID=8YFLogxK

U2 - 10.3987/COM-08-S(F)38

DO - 10.3987/COM-08-S(F)38

M3 - Article

AN - SCOPUS:65549139464

VL - 77

SP - 217

EP - 225

JO - Heterocycles

JF - Heterocycles

SN - 0385-5414

IS - 1

ER -