Tetracyclines for treating multidrug-resistant Acinetobacter baumannii ventilator-associated pneumonia

G Christopher Wood, Scott D. Hanes, Bradley Boucher, Martin Croce, Timothy Fabian

Research output: Contribution to journalArticle

71 Citations (Scopus)

Abstract

Objective: To report the use of tetracyclines for the treatment of multidrug-resistant Acinetobacter baumannii ventilator-associated pneumonia (VAP). Design: Observational case series. Setting: The Presley Regional Trauma Center located within the Regional Medical Center, Memphis, Tennessee, USA. Patients and participants: Seven critically ill trauma patients with VAP caused by A. baumannii isolates that were resistant to all antibiotics tested except for doxycycline or minocycline. Interventions: Patients were treated with IV doxycycline or minocycline for an average of 13.5 (range 9-20) days. Measurements and results: Doxycycline or minocycline was successful in six of seven patients. Conclusions: Doxycycline or minocycline may be effective for treating multidrug-resistant A. baumannii VAP.

Original languageEnglish (US)
Pages (from-to)2072-2076
Number of pages5
JournalIntensive care medicine
Volume29
Issue number11
DOIs
StatePublished - Nov 1 2003

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Ventilator-Associated Pneumonia
Acinetobacter baumannii
Tetracyclines
Minocycline
Doxycycline
Trauma Centers
Critical Illness
Anti-Bacterial Agents
Wounds and Injuries
Therapeutics

All Science Journal Classification (ASJC) codes

  • Critical Care and Intensive Care Medicine

Cite this

Tetracyclines for treating multidrug-resistant Acinetobacter baumannii ventilator-associated pneumonia. / Wood, G Christopher; Hanes, Scott D.; Boucher, Bradley; Croce, Martin; Fabian, Timothy.

In: Intensive care medicine, Vol. 29, No. 11, 01.11.2003, p. 2072-2076.

Research output: Contribution to journalArticle

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