The adult respiratory distress syndrome

Bradley Boucher, T. S. Foster

Research output: Contribution to journalReview article

6 Citations (Scopus)

Abstract

The adult respiratory distress syndrome (ARDS) is a common form of acute respiratory failure that has been increasingly reported as associated with a wide variety of medical conditions. Unlike other identifiable pathological events causing severe lung injury, it is now recognized that ARDS is not a single disease, but a complex interaction of pathophysiological events that result in diffuse injury to lung parenchyma. Only through a thorough understanding of ARDS pathophysiology, pathogenesis, and clinical course can medical intervention be instituted in a judicious and timely manner. This review article is intended to provide an overview of the suspected precipitating causes, discrete pathophysiologic changes, and monitorable clinical events associated with ARDS. With mortality from ARDS high, significant attention is being given to improving therapeutic intervention with such conventional measures as mechanical ventilation, positive end-expiratory pressure, and fluid management, along with corticosteroids and several new experimental pharmacologic approaches.

Original languageEnglish (US)
Pages (from-to)862-868
Number of pages7
JournalDrug Intelligence and Clinical Pharmacy
Volume18
Issue number11
StatePublished - Dec 1 1984

Fingerprint

Adult Respiratory Distress Syndrome
Lung Injury
Positive-Pressure Respiration
Artificial Respiration
Respiratory Insufficiency
Adrenal Cortex Hormones
Mortality

All Science Journal Classification (ASJC) codes

  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Pharmacology (medical)

Cite this

The adult respiratory distress syndrome. / Boucher, Bradley; Foster, T. S.

In: Drug Intelligence and Clinical Pharmacy, Vol. 18, No. 11, 01.12.1984, p. 862-868.

Research output: Contribution to journalReview article

Boucher, Bradley ; Foster, T. S. / The adult respiratory distress syndrome. In: Drug Intelligence and Clinical Pharmacy. 1984 ; Vol. 18, No. 11. pp. 862-868.
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