Kazaklarda endotelin-1 geninin lys198asn polimorfizmi ile arteriyel hipertansiyon gelişme riski arasi{dotless}ndaki ilişki

Translated title of the contribution: The association between polymorphism of lys198asn of endothelin-1 gene and arterial hypertension risk in Kazakh people

A. U. Dzholdasbekova, Abduzhappar Gaipov

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Aim: We researched frequency distribution of genotypes and alleles Lys198Asn of polymorphism of endothelin -1 gene associated with arterial hypertension development in Kazakh people Method: The research included 120 patients suffering arterial hypertension of 2-3 degree, average, high and very high degree of risk, and control group included 80 actually healthy person of Kazakh nationality. Result: The research discovered that development of arterial hypertension in the present ethnic group associated with polymorphism of endothelin-1 gene. Conclusion: At that, allele 198Asn and AsnAsn genotype of endothelin-1 gene act as marker of increased risk of arterial hypertension development.

Original languageTurkish
Pages (from-to)187-191
Number of pages5
JournalEuropean Journal of General Medicine
Volume7
Issue number2
StatePublished - Dec 21 2010

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Endothelin-1
Hypertension
Ethnic Groups
Genes
Alleles
Genotype
Research
Control Groups

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Kazaklarda endotelin-1 geninin lys198asn polimorfizmi ile arteriyel hipertansiyon gelişme riski arasi{dotless}ndaki ilişki. / Dzholdasbekova, A. U.; Gaipov, Abduzhappar.

In: European Journal of General Medicine, Vol. 7, No. 2, 21.12.2010, p. 187-191.

Research output: Contribution to journalArticle

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