The computerized self test (CST)

An interactive, internet accessible cognitive screening test for dementia

John Dougherty, Rex L. Cannon, Christopher R. Nicholas, Lorin Hall, Felicia Hare, Erika Carr, Andrew Dougherty, Jennifer Janowitz, Justin Arunthamakun

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

The computer self test (CST) is an interactive, internet-based instrument designed to assess functional cognitive domains impaired by Alzheimer's disease (AD) and mild cognitive impairment (MCI). This study consisted of 215 total subjects with a mean age of 75.24. The 84 cognitively impaired patients (excluding patients diagnosed as MCI) met all criteria set forth by NINCDS/ADRDA for the diagnosis of AD. Control participants consisted of 104 age-matched individuals who were cognitively unimpaired. All patients completed the CST prior to other routine neurocognitive procedures. The CST accurately classified 96% of the cognitively impaired individuals as compared to controls, while the Mini-Mental Status Examination (MMSE) accurately classified 71% and the Mini-Cog 69% in the same respect. In addition, the CST accurately classified 91% of the six experimental groups (control, MCI, early AD, mild to moderate, moderate to severe, and severe) as compared to 54% for the MMSE and 48% for the Mini-Cog. In conclusions, the CST demonstrates a high degree of sensitivity and specificity and is capable of accurately identifying cognitive impairment in patients with variable degrees of cognitive abnormality. This interactive internet-based cognitive screening tool may aid in early detection of cognitive impairment in the primary care setting. The ease of use and interpretation may also provide the means to obtain an accurate baseline from which to monitor cognitive changes over time.

Original languageEnglish (US)
Pages (from-to)185-195
Number of pages11
JournalJournal of Alzheimer's Disease
Volume20
Issue number1
DOIs
StatePublished - Jan 1 2010

Fingerprint

Internet
Dementia
Alzheimer Disease
Primary Health Care
Cognitive Dysfunction
Sensitivity and Specificity
Control Groups

All Science Journal Classification (ASJC) codes

  • Clinical Psychology
  • Geriatrics and Gerontology
  • Psychiatry and Mental health

Cite this

The computerized self test (CST) : An interactive, internet accessible cognitive screening test for dementia. / Dougherty, John; Cannon, Rex L.; Nicholas, Christopher R.; Hall, Lorin; Hare, Felicia; Carr, Erika; Dougherty, Andrew; Janowitz, Jennifer; Arunthamakun, Justin.

In: Journal of Alzheimer's Disease, Vol. 20, No. 1, 01.01.2010, p. 185-195.

Research output: Contribution to journalArticle

Dougherty, J, Cannon, RL, Nicholas, CR, Hall, L, Hare, F, Carr, E, Dougherty, A, Janowitz, J & Arunthamakun, J 2010, 'The computerized self test (CST): An interactive, internet accessible cognitive screening test for dementia', Journal of Alzheimer's Disease, vol. 20, no. 1, pp. 185-195. https://doi.org/10.3233/JAD-2010-1354
Dougherty, John ; Cannon, Rex L. ; Nicholas, Christopher R. ; Hall, Lorin ; Hare, Felicia ; Carr, Erika ; Dougherty, Andrew ; Janowitz, Jennifer ; Arunthamakun, Justin. / The computerized self test (CST) : An interactive, internet accessible cognitive screening test for dementia. In: Journal of Alzheimer's Disease. 2010 ; Vol. 20, No. 1. pp. 185-195.
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