The CYPome (Cytochrome P450 complement) of Aspergillus nidulans.

Diane E. Kelly, Nada Krasevec, Jonathan Mullins, David Nelson

Research output: Contribution to journalArticle

55 Citations (Scopus)

Abstract

The cytochromes P450 (CYPs) are found in all biological kingdoms and genome sequencing projects continue to reveal an ever increasing number. The principle aim of this paper is to identify the complete CYPome of Aspergillus nidulans from the genome sequence version AN.3 deposited at the Broad institute, assign the appropriate CYP nomenclature and define function where possible. The completed analysis revealed a total of 111 CYP genes, 3 of which were previously unknown and 8 pseudogenes, representing 89CYP families, 21 of which are unique. We have identified 28 potential gene clusters associated with one or more CYP genes and discussed those with putative PKS and NRPS associated function. The chromosomal location of the genes, predicted cellular location of the proteins and possible function(s) are discussed.

Original languageEnglish (US)
JournalFungal genetics and biology : FG & B
Volume46 Suppl 1
DOIs
StatePublished - Jan 1 2009
Externally publishedYes

Fingerprint

Aspergillus nidulans
Cytochrome P-450 Enzyme System
Genome
Genes
Pseudogenes
Multigene Family
Terminology
Proteins

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Genetics

Cite this

The CYPome (Cytochrome P450 complement) of Aspergillus nidulans. / Kelly, Diane E.; Krasevec, Nada; Mullins, Jonathan; Nelson, David.

In: Fungal genetics and biology : FG & B, Vol. 46 Suppl 1, 01.01.2009.

Research output: Contribution to journalArticle

Kelly, Diane E. ; Krasevec, Nada ; Mullins, Jonathan ; Nelson, David. / The CYPome (Cytochrome P450 complement) of Aspergillus nidulans. In: Fungal genetics and biology : FG & B. 2009 ; Vol. 46 Suppl 1.
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