The effect of monochromatic infrared energy on sensation in patients with diabetic peripheral neuropathy

A double-blind, placebo-controlled study

Judy Clifft, Richard Kasser, Timothy S. Newton, Andrew J. Bush

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

OBJECTIVE - The purpose of this study was to determine the effect of monochromatic infrared energy (MIRE) on plantar sensation in subjects with diabetic peripheral neuropathy. RESEARCH DESIGN AND METHODS - In this randomized, double-blind, placebo-controlled study, 39 subjects with diabetic peripheral neuropathy completed the 8-week study. Subjects received 30 min of active or placebo MIRE three times a week for 4 weeks. Plantar sensation was tested with monofilaments at the beginning of the study (M1), following 4 weeks of treatment (M2), and after an additional 4 weeks of nontreatment (M3). The number of sites that could sense the 5.07 monofilament was totaled at M1, M2, and M3. Data were analyzed using a special repeated-measures statistic followed by a post hoc Tukey-Kramer test. RESULTS - The average number of sites that patients could sense the 5.07 monofilament increased for both the active and placebo groups. There were significant gains from M1 to M2 (P < 0.002), no significant gains from M2 to M3 (P = 0.234), and significant gains from M1 to M3 (P < 0.002) for both the active and placebo groups. There were no significant differences between active and placebo groups at any measurement. CONCLUSIONS - Thirty minutes of active MIRE applied 3 days per week for 4 weeks was no more effective than placebo MIRE in increasing sensation in subjects with diabetic peripheral neuropathy. Clinicians should be aware that MIRE may not be an effective modality for improving sensory impairments in patients with diabetic neuropathy.

Original languageEnglish (US)
Pages (from-to)2896-2900
Number of pages5
JournalDiabetes care
Volume28
Issue number12
DOIs
StatePublished - Dec 1 2005

Fingerprint

Diabetic Neuropathies
Peripheral Nervous System Diseases
Placebos
Research Design

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Advanced and Specialized Nursing

Cite this

The effect of monochromatic infrared energy on sensation in patients with diabetic peripheral neuropathy : A double-blind, placebo-controlled study. / Clifft, Judy; Kasser, Richard; Newton, Timothy S.; Bush, Andrew J.

In: Diabetes care, Vol. 28, No. 12, 01.12.2005, p. 2896-2900.

Research output: Contribution to journalArticle

@article{178bfeba8809484e9fa5e9090abc44d9,
title = "The effect of monochromatic infrared energy on sensation in patients with diabetic peripheral neuropathy: A double-blind, placebo-controlled study",
abstract = "OBJECTIVE - The purpose of this study was to determine the effect of monochromatic infrared energy (MIRE) on plantar sensation in subjects with diabetic peripheral neuropathy. RESEARCH DESIGN AND METHODS - In this randomized, double-blind, placebo-controlled study, 39 subjects with diabetic peripheral neuropathy completed the 8-week study. Subjects received 30 min of active or placebo MIRE three times a week for 4 weeks. Plantar sensation was tested with monofilaments at the beginning of the study (M1), following 4 weeks of treatment (M2), and after an additional 4 weeks of nontreatment (M3). The number of sites that could sense the 5.07 monofilament was totaled at M1, M2, and M3. Data were analyzed using a special repeated-measures statistic followed by a post hoc Tukey-Kramer test. RESULTS - The average number of sites that patients could sense the 5.07 monofilament increased for both the active and placebo groups. There were significant gains from M1 to M2 (P < 0.002), no significant gains from M2 to M3 (P = 0.234), and significant gains from M1 to M3 (P < 0.002) for both the active and placebo groups. There were no significant differences between active and placebo groups at any measurement. CONCLUSIONS - Thirty minutes of active MIRE applied 3 days per week for 4 weeks was no more effective than placebo MIRE in increasing sensation in subjects with diabetic peripheral neuropathy. Clinicians should be aware that MIRE may not be an effective modality for improving sensory impairments in patients with diabetic neuropathy.",
author = "Judy Clifft and Richard Kasser and Newton, {Timothy S.} and Bush, {Andrew J.}",
year = "2005",
month = "12",
day = "1",
doi = "10.2337/diacare.28.12.2896",
language = "English (US)",
volume = "28",
pages = "2896--2900",
journal = "Diabetes Care",
issn = "1935-5548",
publisher = "American Diabetes Association Inc.",
number = "12",

}

TY - JOUR

T1 - The effect of monochromatic infrared energy on sensation in patients with diabetic peripheral neuropathy

T2 - A double-blind, placebo-controlled study

AU - Clifft, Judy

AU - Kasser, Richard

AU - Newton, Timothy S.

AU - Bush, Andrew J.

PY - 2005/12/1

Y1 - 2005/12/1

N2 - OBJECTIVE - The purpose of this study was to determine the effect of monochromatic infrared energy (MIRE) on plantar sensation in subjects with diabetic peripheral neuropathy. RESEARCH DESIGN AND METHODS - In this randomized, double-blind, placebo-controlled study, 39 subjects with diabetic peripheral neuropathy completed the 8-week study. Subjects received 30 min of active or placebo MIRE three times a week for 4 weeks. Plantar sensation was tested with monofilaments at the beginning of the study (M1), following 4 weeks of treatment (M2), and after an additional 4 weeks of nontreatment (M3). The number of sites that could sense the 5.07 monofilament was totaled at M1, M2, and M3. Data were analyzed using a special repeated-measures statistic followed by a post hoc Tukey-Kramer test. RESULTS - The average number of sites that patients could sense the 5.07 monofilament increased for both the active and placebo groups. There were significant gains from M1 to M2 (P < 0.002), no significant gains from M2 to M3 (P = 0.234), and significant gains from M1 to M3 (P < 0.002) for both the active and placebo groups. There were no significant differences between active and placebo groups at any measurement. CONCLUSIONS - Thirty minutes of active MIRE applied 3 days per week for 4 weeks was no more effective than placebo MIRE in increasing sensation in subjects with diabetic peripheral neuropathy. Clinicians should be aware that MIRE may not be an effective modality for improving sensory impairments in patients with diabetic neuropathy.

AB - OBJECTIVE - The purpose of this study was to determine the effect of monochromatic infrared energy (MIRE) on plantar sensation in subjects with diabetic peripheral neuropathy. RESEARCH DESIGN AND METHODS - In this randomized, double-blind, placebo-controlled study, 39 subjects with diabetic peripheral neuropathy completed the 8-week study. Subjects received 30 min of active or placebo MIRE three times a week for 4 weeks. Plantar sensation was tested with monofilaments at the beginning of the study (M1), following 4 weeks of treatment (M2), and after an additional 4 weeks of nontreatment (M3). The number of sites that could sense the 5.07 monofilament was totaled at M1, M2, and M3. Data were analyzed using a special repeated-measures statistic followed by a post hoc Tukey-Kramer test. RESULTS - The average number of sites that patients could sense the 5.07 monofilament increased for both the active and placebo groups. There were significant gains from M1 to M2 (P < 0.002), no significant gains from M2 to M3 (P = 0.234), and significant gains from M1 to M3 (P < 0.002) for both the active and placebo groups. There were no significant differences between active and placebo groups at any measurement. CONCLUSIONS - Thirty minutes of active MIRE applied 3 days per week for 4 weeks was no more effective than placebo MIRE in increasing sensation in subjects with diabetic peripheral neuropathy. Clinicians should be aware that MIRE may not be an effective modality for improving sensory impairments in patients with diabetic neuropathy.

UR - http://www.scopus.com/inward/record.url?scp=33644819294&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33644819294&partnerID=8YFLogxK

U2 - 10.2337/diacare.28.12.2896

DO - 10.2337/diacare.28.12.2896

M3 - Article

VL - 28

SP - 2896

EP - 2900

JO - Diabetes Care

JF - Diabetes Care

SN - 1935-5548

IS - 12

ER -