The effect of somatostatin on platelet aggregation1

T. M. Chiang, W. C. Duckworth, E. H. Beachey, Andrew Kang

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Somatostatin was infused intravenously over two hours to rabbits in a dose of 1.5 μg/kg/min with an. initial loading dose of 50 μg/kg. This dose inhibited platelet aggregation in response to both ADP and collagen. Lower doses of SRIFhad no effect. The addition of SRIF in vitro to either human or rabbit platelet rich plasma also had no effect on collagen or ADP-induced platelet aggregation.

Original languageEnglish (US)
Pages (from-to)753-756
Number of pages4
JournalEndocrinology
Volume97
Issue number3
DOIs
StatePublished - Jan 1 1975

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Somatostatin
Platelet Aggregation
Adenosine Diphosphate
Collagen
Blood Platelets
Rabbits
Platelet-Rich Plasma
In Vitro Techniques

All Science Journal Classification (ASJC) codes

  • Endocrinology

Cite this

Chiang, T. M., Duckworth, W. C., Beachey, E. H., & Kang, A. (1975). The effect of somatostatin on platelet aggregation1. Endocrinology, 97(3), 753-756. https://doi.org/10.1210/endo-97-3-753

The effect of somatostatin on platelet aggregation1. / Chiang, T. M.; Duckworth, W. C.; Beachey, E. H.; Kang, Andrew.

In: Endocrinology, Vol. 97, No. 3, 01.01.1975, p. 753-756.

Research output: Contribution to journalArticle

Chiang, TM, Duckworth, WC, Beachey, EH & Kang, A 1975, 'The effect of somatostatin on platelet aggregation1', Endocrinology, vol. 97, no. 3, pp. 753-756. https://doi.org/10.1210/endo-97-3-753
Chiang, T. M. ; Duckworth, W. C. ; Beachey, E. H. ; Kang, Andrew. / The effect of somatostatin on platelet aggregation1. In: Endocrinology. 1975 ; Vol. 97, No. 3. pp. 753-756.
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