The effect of standardizing treatment when managing neonatal abstinence syndrome*

Tara Burnette, Lindsey Chernicky, Craig Towers

Research output: Contribution to journalArticle

Abstract

Objective: Standardizing treatment of neonatal abstinence syndrome (NAS) is currently recommended; however, single institution prospective studies are lacking regarding the success of this approach. The study objective was to evaluate overall newborn response and length of stay (LOS) of neonates treated for NAS following the institution of a strict standardized treatment protocol. Methods: From 1 January 2014 to 30 June 2016, a prospective cohort study was performed collecting neonatal outcomes before and after the standardization of a strict NAS morphine weaning treatment protocol. The primary outcome measure was length of stay. The standardized protocol was fully instituted in June 2015. Results: A total of 395 neonates were treated for NAS during the study. The LOS for the 17 months prior to the initiation of this protocol was 23.31 (±6.2) days (233 neonates). The LOS in the 13 months after protocol initiation was 18.17 (±5.1) days (162 neonates). This was a difference of 5.14 days (95%CI 4.0–6.3 days) less in LOS (p <.0001). Conclusions: These data demonstrate that the initiation of a standardized NAS treatment protocol can significantly improve neonatal response and decrease LOS. It is recommended that institutions with nurseries that treat infants with NAS develop standardized treatment protocols to improve care for this complicated patient population.

Original languageEnglish (US)
Pages (from-to)3415-3419
Number of pages5
JournalJournal of Maternal-Fetal and Neonatal Medicine
Volume32
Issue number20
DOIs
StatePublished - Oct 18 2019

Fingerprint

Neonatal Abstinence Syndrome
Length of Stay
Clinical Protocols
Newborn Infant
Therapeutics
Prospective Studies
Nurseries
Weaning
Morphine
Patient Care
Cohort Studies
Outcome Assessment (Health Care)

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

Cite this

The effect of standardizing treatment when managing neonatal abstinence syndrome*. / Burnette, Tara; Chernicky, Lindsey; Towers, Craig.

In: Journal of Maternal-Fetal and Neonatal Medicine, Vol. 32, No. 20, 18.10.2019, p. 3415-3419.

Research output: Contribution to journalArticle

@article{0a181d2b782749b0a937b59b3cfe9e1e,
title = "The effect of standardizing treatment when managing neonatal abstinence syndrome*",
abstract = "Objective: Standardizing treatment of neonatal abstinence syndrome (NAS) is currently recommended; however, single institution prospective studies are lacking regarding the success of this approach. The study objective was to evaluate overall newborn response and length of stay (LOS) of neonates treated for NAS following the institution of a strict standardized treatment protocol. Methods: From 1 January 2014 to 30 June 2016, a prospective cohort study was performed collecting neonatal outcomes before and after the standardization of a strict NAS morphine weaning treatment protocol. The primary outcome measure was length of stay. The standardized protocol was fully instituted in June 2015. Results: A total of 395 neonates were treated for NAS during the study. The LOS for the 17 months prior to the initiation of this protocol was 23.31 (±6.2) days (233 neonates). The LOS in the 13 months after protocol initiation was 18.17 (±5.1) days (162 neonates). This was a difference of 5.14 days (95{\%}CI 4.0–6.3 days) less in LOS (p <.0001). Conclusions: These data demonstrate that the initiation of a standardized NAS treatment protocol can significantly improve neonatal response and decrease LOS. It is recommended that institutions with nurseries that treat infants with NAS develop standardized treatment protocols to improve care for this complicated patient population.",
author = "Tara Burnette and Lindsey Chernicky and Craig Towers",
year = "2019",
month = "10",
day = "18",
doi = "10.1080/14767058.2018.1465038",
language = "English (US)",
volume = "32",
pages = "3415--3419",
journal = "Journal of Maternal-Fetal and Neonatal Medicine",
issn = "1476-7058",
publisher = "Informa Healthcare",
number = "20",

}

TY - JOUR

T1 - The effect of standardizing treatment when managing neonatal abstinence syndrome*

AU - Burnette, Tara

AU - Chernicky, Lindsey

AU - Towers, Craig

PY - 2019/10/18

Y1 - 2019/10/18

N2 - Objective: Standardizing treatment of neonatal abstinence syndrome (NAS) is currently recommended; however, single institution prospective studies are lacking regarding the success of this approach. The study objective was to evaluate overall newborn response and length of stay (LOS) of neonates treated for NAS following the institution of a strict standardized treatment protocol. Methods: From 1 January 2014 to 30 June 2016, a prospective cohort study was performed collecting neonatal outcomes before and after the standardization of a strict NAS morphine weaning treatment protocol. The primary outcome measure was length of stay. The standardized protocol was fully instituted in June 2015. Results: A total of 395 neonates were treated for NAS during the study. The LOS for the 17 months prior to the initiation of this protocol was 23.31 (±6.2) days (233 neonates). The LOS in the 13 months after protocol initiation was 18.17 (±5.1) days (162 neonates). This was a difference of 5.14 days (95%CI 4.0–6.3 days) less in LOS (p <.0001). Conclusions: These data demonstrate that the initiation of a standardized NAS treatment protocol can significantly improve neonatal response and decrease LOS. It is recommended that institutions with nurseries that treat infants with NAS develop standardized treatment protocols to improve care for this complicated patient population.

AB - Objective: Standardizing treatment of neonatal abstinence syndrome (NAS) is currently recommended; however, single institution prospective studies are lacking regarding the success of this approach. The study objective was to evaluate overall newborn response and length of stay (LOS) of neonates treated for NAS following the institution of a strict standardized treatment protocol. Methods: From 1 January 2014 to 30 June 2016, a prospective cohort study was performed collecting neonatal outcomes before and after the standardization of a strict NAS morphine weaning treatment protocol. The primary outcome measure was length of stay. The standardized protocol was fully instituted in June 2015. Results: A total of 395 neonates were treated for NAS during the study. The LOS for the 17 months prior to the initiation of this protocol was 23.31 (±6.2) days (233 neonates). The LOS in the 13 months after protocol initiation was 18.17 (±5.1) days (162 neonates). This was a difference of 5.14 days (95%CI 4.0–6.3 days) less in LOS (p <.0001). Conclusions: These data demonstrate that the initiation of a standardized NAS treatment protocol can significantly improve neonatal response and decrease LOS. It is recommended that institutions with nurseries that treat infants with NAS develop standardized treatment protocols to improve care for this complicated patient population.

UR - http://www.scopus.com/inward/record.url?scp=85062948882&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85062948882&partnerID=8YFLogxK

U2 - 10.1080/14767058.2018.1465038

DO - 10.1080/14767058.2018.1465038

M3 - Article

VL - 32

SP - 3415

EP - 3419

JO - Journal of Maternal-Fetal and Neonatal Medicine

JF - Journal of Maternal-Fetal and Neonatal Medicine

SN - 1476-7058

IS - 20

ER -