The effects of in utero cocaine-exposure on the heart rate and heart rate variability of near and full term infants following orthostatic stress

Vijay John, M. R. Neuman, Ajay Talati, H. Bada

Research output: Contribution to journalConference article

Abstract

To understand the effects of in utero cocaine exposure on the developing fetus, we studied the heart rate and the heart rate variability (HRV) in near and full term cocaine-exposed infants during quiet sleep supine and following orthostatic stress. 21 cocaine-exposed and 23 control infants were studied within 120 hours of birth. 30-minute segments of the electrocardiogram (ECG) were recorded with the infant, horizontal followed by the infant in a 25° head-up tilt. The cocaine-exposed group, as compared with the control group, had a trend toward an increase in heart rate in the horizontal position and a significant increase in heart rate following the tilt. The frequency components of the heart rate were lower in the horizontal position and increased following the orthostatic stress. These results are consistent with the known pharmacological actions of cocaine and demonstrate the possible adverse neonatal effects of cocaine abuse during pregnancy.

Original languageEnglish (US)
Pages (from-to)97-99
Number of pages3
JournalComputers in Cardiology
Volume29
StatePublished - Dec 1 2002
EventComputers in Cardiology 2002 - Memphis, TN, United States
Duration: Sep 22 2002Sep 25 2002

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Cocaine
Heart Rate
Cocaine-Related Disorders
Electrocardiography
Sleep
Fetus
Head
Parturition
Pharmacology
Pregnancy
Control Groups

All Science Journal Classification (ASJC) codes

  • Computer Science Applications
  • Cardiology and Cardiovascular Medicine

Cite this

The effects of in utero cocaine-exposure on the heart rate and heart rate variability of near and full term infants following orthostatic stress. / John, Vijay; Neuman, M. R.; Talati, Ajay; Bada, H.

In: Computers in Cardiology, Vol. 29, 01.12.2002, p. 97-99.

Research output: Contribution to journalConference article

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