The effects of season and alcohol intake on mineral metabolism in men

Horace M. Perry, Michael Horowitz, Shantiel Fleming, Fran E. Kaiser, Ping Patrick, John E. Morley, William Cushman, Stephen Bingham, H. M. Perry

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

We have examined the relationship between self-reported alcohol intake (SRAI), season and mineral metabolism in a series of 96 men aged 32 to 78 years of age. Alcohol intake was reported as between 0 and 50% oz/week. SRAI correlated positively with liver function tests, including serum bilirubin, alkaline phosphatase, and AST initially and at 6 months. In addition, SRAI correlated with serum calcium, testosterone, estradiol, and immunoreactive parathyroid hormone (iPTH) as well as urinary calcium [per 100 mg of creatinine (Cr)], and pyridinoline crosslinks (DPC) (per 100 mg of Cr). We have divided the participants into two groups on the basis of their reported alcohol intake. Individuals with none-to-moderate intake had <8.4 oz/week of ethanol. Those with moderate or heavier intake had 8.4 oz or more of ethanol/week. Individuals with none-to-moderate SRAI had a significant seasonal increase in iPTH, osteocalcin, urine DPC/100 mg of Cr and a decrease in distal forearm bone mineral density, 25 hydroxyvitamin D (250HD), and urinary calcium/100 mg of Cr. Individuals with moderate or heavier SRAI only had significant seasonal decrease in 250HD. We have concluded that alcohol intake decreases seasonal change in serum iPTH. The biological effects of such alterations in parathyroid hormone levels include decreased seasonal loss of bone mineral density.

Original languageEnglish (US)
Pages (from-to)214-219
Number of pages6
JournalAlcoholism: Clinical and Experimental Research
Volume23
Issue number2
DOIs
StatePublished - Jan 1 1999

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Metabolism
Minerals
Alcohols
Parathyroid Hormone
Creatinine
Calcium
Bone Density
Bone
Ethanol
Serum
Liver Function Tests
Osteocalcin
Bilirubin
Forearm
Liver
Alkaline Phosphatase
Testosterone
Estradiol
Urine

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Toxicology
  • Psychiatry and Mental health

Cite this

Perry, H. M., Horowitz, M., Fleming, S., Kaiser, F. E., Patrick, P., Morley, J. E., ... Perry, H. M. (1999). The effects of season and alcohol intake on mineral metabolism in men. Alcoholism: Clinical and Experimental Research, 23(2), 214-219. https://doi.org/10.1111/j.1530-0277.1999.tb04102.x

The effects of season and alcohol intake on mineral metabolism in men. / Perry, Horace M.; Horowitz, Michael; Fleming, Shantiel; Kaiser, Fran E.; Patrick, Ping; Morley, John E.; Cushman, William; Bingham, Stephen; Perry, H. M.

In: Alcoholism: Clinical and Experimental Research, Vol. 23, No. 2, 01.01.1999, p. 214-219.

Research output: Contribution to journalArticle

Perry, HM, Horowitz, M, Fleming, S, Kaiser, FE, Patrick, P, Morley, JE, Cushman, W, Bingham, S & Perry, HM 1999, 'The effects of season and alcohol intake on mineral metabolism in men', Alcoholism: Clinical and Experimental Research, vol. 23, no. 2, pp. 214-219. https://doi.org/10.1111/j.1530-0277.1999.tb04102.x
Perry, Horace M. ; Horowitz, Michael ; Fleming, Shantiel ; Kaiser, Fran E. ; Patrick, Ping ; Morley, John E. ; Cushman, William ; Bingham, Stephen ; Perry, H. M. / The effects of season and alcohol intake on mineral metabolism in men. In: Alcoholism: Clinical and Experimental Research. 1999 ; Vol. 23, No. 2. pp. 214-219.
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