The Gut Microbiota

The Gateway to Improved Metabolism

Kristina B. Martinez, Joseph Pierre, Eugene B. Chang

Research output: Contribution to journalReview article

11 Citations (Scopus)

Abstract

Obesity is an emerging global epidemic with profound challenges to world health care economies and societies. Traditional approaches to fighting obesity have not shown promise in promoting a decline in obesity prevalence. The gut microbiota is becoming widely appreciated for its role in regulating metabolism and thus represents a target for new therapies to combat obesity and associated comorbidities. This article provides an overview of altered microbial community structure in obesity, dietary impact on the gut microbiota, host-microbe interactions contributing to the disease, and improvements in microbial assemblage after bariatric surgery and with therapies targeting the gut microbiome.

Original languageEnglish (US)
Pages (from-to)601-614
Number of pages14
JournalGastroenterology Clinics of North America
Volume45
Issue number4
DOIs
StatePublished - Dec 1 2016

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Obesity
Bariatric Surgery
Comorbidity
Gastrointestinal Microbiome
Delivery of Health Care
Therapeutics

All Science Journal Classification (ASJC) codes

  • Gastroenterology

Cite this

The Gut Microbiota : The Gateway to Improved Metabolism. / Martinez, Kristina B.; Pierre, Joseph; Chang, Eugene B.

In: Gastroenterology Clinics of North America, Vol. 45, No. 4, 01.12.2016, p. 601-614.

Research output: Contribution to journalReview article

Martinez, Kristina B. ; Pierre, Joseph ; Chang, Eugene B. / The Gut Microbiota : The Gateway to Improved Metabolism. In: Gastroenterology Clinics of North America. 2016 ; Vol. 45, No. 4. pp. 601-614.
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