The Important Role of Inflammatory Biomarkers Pre and Post Bare-Metal and Drug-Eluting Stent Implantation

Rami Khouzam, Mazen Shaheen, Ramy K. Aziz, Uzoma Ibebuogu

Research output: Contribution to journalReview article

20 Citations (Scopus)

Abstract

In-stent restenosis and stent thrombosis are major complications after percutaneous coronary intervention and coronary stent placement. The inflammatory status of an individual, as reflected by biomarkers and genetic polymorphisms, is a strong predictor of the risk of in-stent restenosis and stent thrombosis. Identifying biomarkers and studying their values are crucial for a more efficient personalized intervention. General inflammatory biomarkers, evidence of inflammation, and the difference between inflammatory biomarkers after bare-metal stent and drug-eluting stent placement are discussed. Clinical implications and the use of antiplatelet and anti-inflammatory medications, as well as future directions in coronary intervention, in reducing the occurrence of these complications, are also discussed.

Original languageEnglish (US)
Pages (from-to)700-705
Number of pages6
JournalCanadian Journal of Cardiology
Volume28
Issue number6
DOIs
StatePublished - Nov 1 2012

Fingerprint

Drug-Eluting Stents
Stents
Biomarkers
Metals
Thrombosis
Genetic Polymorphisms
Percutaneous Coronary Intervention
Anti-Inflammatory Agents
Inflammation

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

The Important Role of Inflammatory Biomarkers Pre and Post Bare-Metal and Drug-Eluting Stent Implantation. / Khouzam, Rami; Shaheen, Mazen; Aziz, Ramy K.; Ibebuogu, Uzoma.

In: Canadian Journal of Cardiology, Vol. 28, No. 6, 01.11.2012, p. 700-705.

Research output: Contribution to journalReview article

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