The influence of physical activity and sedentary behavior on living to age 85 years without disease and disability in older women

Eileen Rillamas-Sun, Michael J. Lamonte, Kelly R. Evenson, Cynthia A. Thomson, Shirley A. Beresford, Mathilda Coday, Todd M. Manini, Wenjun Li, Andrea Z. Lacroix

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background Whether physical activity (PA) and sedentary behavior influence the odds of women living to age 85 years without chronic disease or disability is not well described. Methods Participants of the Women's Health Initiative (n = 49,612) were categorized based on health status by age 85 years: (i) lived without developing major chronic disease or mobility disability ("healthy"); (ii) lived and developed mobility disability with or without disease; (iii) lived and developed major chronic disease, but not mobility disability; and (iv) died before their 85th birth year. Multinomial logistic regression models that adjusted for covariates such as age, race/ethnicity, and body size estimated associations of self-reported PA and sitting time on developing major disease or mobility disability or dying before age 85 relative to being healthy. Results Mean ± SD baseline age was 70.2 ± 3.6 years. Distributions were: 22% healthy, 23% had mobility disability, 26% had major disease, and 29% died. Relative to those with high total PA, the adjusted odds ratios (OR) (confidence intervals [CI]) for mobility disability was 1.6 (1.4-1.7), 1.2 (1.1-1.3), and 1.1 (1.0-1.2) for women with no, low, and moderate total PA, respectively (p-trend <.001). The corresponding covariate-adjusted OR (CI) for mortality was 1.7 (1.5-1.8), 1.2 (1.1-1.3), and 1.0 (1.0-1.1) (p-trend <.001). Total PA was not associated with developing chronic disease before age 85 years. Sitting ≥10 relative to <5 hours per day increased the odds of mobility disability (1.1, CI: 1.0-1.3) and mortality (1.2, CI: 1.0-1.3) prior to age 85 years (p <.001). Conclusions Increasing PA to recommended levels and reducing sitting time are modifiable behaviors that may improve healthy aging in older women.

Original languageEnglish (US)
Pages (from-to)1525-1531
Number of pages7
JournalJournals of Gerontology - Series A Biological Sciences and Medical Sciences
Volume73
Issue number11
DOIs
StatePublished - Oct 8 2018

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Exercise
Chronic Disease
Confidence Intervals
Logistic Models
Odds Ratio
Mortality
Body Size
Women's Health
Health Status
Parturition

All Science Journal Classification (ASJC) codes

  • Aging
  • Geriatrics and Gerontology

Cite this

The influence of physical activity and sedentary behavior on living to age 85 years without disease and disability in older women. / Rillamas-Sun, Eileen; Lamonte, Michael J.; Evenson, Kelly R.; Thomson, Cynthia A.; Beresford, Shirley A.; Coday, Mathilda; Manini, Todd M.; Li, Wenjun; Lacroix, Andrea Z.

In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences, Vol. 73, No. 11, 08.10.2018, p. 1525-1531.

Research output: Contribution to journalArticle

Rillamas-Sun, Eileen ; Lamonte, Michael J. ; Evenson, Kelly R. ; Thomson, Cynthia A. ; Beresford, Shirley A. ; Coday, Mathilda ; Manini, Todd M. ; Li, Wenjun ; Lacroix, Andrea Z. / The influence of physical activity and sedentary behavior on living to age 85 years without disease and disability in older women. In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 2018 ; Vol. 73, No. 11. pp. 1525-1531.
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T1 - The influence of physical activity and sedentary behavior on living to age 85 years without disease and disability in older women

AU - Rillamas-Sun, Eileen

AU - Lamonte, Michael J.

AU - Evenson, Kelly R.

AU - Thomson, Cynthia A.

AU - Beresford, Shirley A.

AU - Coday, Mathilda

AU - Manini, Todd M.

AU - Li, Wenjun

AU - Lacroix, Andrea Z.

PY - 2018/10/8

Y1 - 2018/10/8

N2 - Background Whether physical activity (PA) and sedentary behavior influence the odds of women living to age 85 years without chronic disease or disability is not well described. Methods Participants of the Women's Health Initiative (n = 49,612) were categorized based on health status by age 85 years: (i) lived without developing major chronic disease or mobility disability ("healthy"); (ii) lived and developed mobility disability with or without disease; (iii) lived and developed major chronic disease, but not mobility disability; and (iv) died before their 85th birth year. Multinomial logistic regression models that adjusted for covariates such as age, race/ethnicity, and body size estimated associations of self-reported PA and sitting time on developing major disease or mobility disability or dying before age 85 relative to being healthy. Results Mean ± SD baseline age was 70.2 ± 3.6 years. Distributions were: 22% healthy, 23% had mobility disability, 26% had major disease, and 29% died. Relative to those with high total PA, the adjusted odds ratios (OR) (confidence intervals [CI]) for mobility disability was 1.6 (1.4-1.7), 1.2 (1.1-1.3), and 1.1 (1.0-1.2) for women with no, low, and moderate total PA, respectively (p-trend <.001). The corresponding covariate-adjusted OR (CI) for mortality was 1.7 (1.5-1.8), 1.2 (1.1-1.3), and 1.0 (1.0-1.1) (p-trend <.001). Total PA was not associated with developing chronic disease before age 85 years. Sitting ≥10 relative to <5 hours per day increased the odds of mobility disability (1.1, CI: 1.0-1.3) and mortality (1.2, CI: 1.0-1.3) prior to age 85 years (p <.001). Conclusions Increasing PA to recommended levels and reducing sitting time are modifiable behaviors that may improve healthy aging in older women.

AB - Background Whether physical activity (PA) and sedentary behavior influence the odds of women living to age 85 years without chronic disease or disability is not well described. Methods Participants of the Women's Health Initiative (n = 49,612) were categorized based on health status by age 85 years: (i) lived without developing major chronic disease or mobility disability ("healthy"); (ii) lived and developed mobility disability with or without disease; (iii) lived and developed major chronic disease, but not mobility disability; and (iv) died before their 85th birth year. Multinomial logistic regression models that adjusted for covariates such as age, race/ethnicity, and body size estimated associations of self-reported PA and sitting time on developing major disease or mobility disability or dying before age 85 relative to being healthy. Results Mean ± SD baseline age was 70.2 ± 3.6 years. Distributions were: 22% healthy, 23% had mobility disability, 26% had major disease, and 29% died. Relative to those with high total PA, the adjusted odds ratios (OR) (confidence intervals [CI]) for mobility disability was 1.6 (1.4-1.7), 1.2 (1.1-1.3), and 1.1 (1.0-1.2) for women with no, low, and moderate total PA, respectively (p-trend <.001). The corresponding covariate-adjusted OR (CI) for mortality was 1.7 (1.5-1.8), 1.2 (1.1-1.3), and 1.0 (1.0-1.1) (p-trend <.001). Total PA was not associated with developing chronic disease before age 85 years. Sitting ≥10 relative to <5 hours per day increased the odds of mobility disability (1.1, CI: 1.0-1.3) and mortality (1.2, CI: 1.0-1.3) prior to age 85 years (p <.001). Conclusions Increasing PA to recommended levels and reducing sitting time are modifiable behaviors that may improve healthy aging in older women.

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