The potential and challenges of using stem cells for cardiovascular repair and regeneration

Qisi Sun, Zhonge Zhang, Zhongjie Sun

Research output: Contribution to journalReview article

26 Citations (Scopus)

Abstract

Recent progress in using stem cells for tissue repair and functional restoration has aroused much attention due to its potential to provide a cue for many diseases such as myocardial infarction. Stem cell therapy for cardiovascular disease has been studied extensively at both experimental and clinical levels. Pluripotent stem cells and mesenchymal stem cells were proven to be effective for myocardial regeneration, angiogenesis, and cardiac functional restoration. In this review, we will concisely discuss advantages and disadvantages of currently-used stem cells for cardiovascular repair and regeneration. The limitations and uniqueness of some types of stem cells will also be discussed. Although substantial progress has been made over the last decade about stem cells in cardiovascular regeneration, many challenges lie ahead before the therapeutic potentials of stem cells can be fully recognized.

Original languageEnglish (US)
Pages (from-to)113-119
Number of pages7
JournalGenes and Diseases
Volume1
Issue number1
DOIs
StatePublished - Sep 1 2014

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Stem cells
Regeneration
Repair
Stem Cells
Restoration
Pluripotent Stem Cells
Cell- and Tissue-Based Therapy
Mesenchymal Stromal Cells
Cues
Cardiovascular Diseases
Myocardial Infarction
Tissue

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology
  • Genetics(clinical)
  • Cell Biology

Cite this

The potential and challenges of using stem cells for cardiovascular repair and regeneration. / Sun, Qisi; Zhang, Zhonge; Sun, Zhongjie.

In: Genes and Diseases, Vol. 1, No. 1, 01.09.2014, p. 113-119.

Research output: Contribution to journalReview article

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