The preliminary report of pathological changes of epiretinal membranes and internal limiting membrane removed during idiopathic macular hole surgery.

Jiaqing Li, Shibo Tang, Yan Luo, Jie Zhang, Shaofen Lin

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

PURPOSE: To investigate the pathological changes of epiretinal membranes (ERM) and internal limiting membrane (ILM) removed during idiopathic macular hole surgery. METHODS: Ten consecutive patients with a unilateral idiopathic macular hole underwent pars plana vitrectomy (PPV) with the surgical removal of the ERMs overlying the hole and ILM surrounding the hole. The pathological features of the excised tissues were examined under the microscope. RESULTS: According to the morphological changes, four ERMs showed cellular elements which looked like glia cells, macrophages, plasma cells, lymphocytes and fibroblast cells. Two of the ILM appeared as transparent membranes without cellular elements. The other eight ILM showed cellular elements on the transparent membranes. CONCLUSION: Our study supports the hypothesis that the tangential traction of vitreous and proliferative cellular elements on the inner surface of ILM causes idiopathic macular holes. Removal of the posterior cortical vitreous, ILM and proliferative cellular tissue is a valid treatment for IMH.

Original languageEnglish (US)
Pages (from-to)143-146
Number of pages4
JournalYan ke xue bao = Eye science / "Yan ke xue bao" bian ji bu
Volume18
Issue number3
StatePublished - Jan 1 2002
Externally publishedYes

Fingerprint

Epiretinal Membrane
Retinal Perforations
Membranes
Temazepam
Vitrectomy
Traction
Plasma Cells
Neuroglia
Fibroblasts
Macrophages
Lymphocytes

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

The preliminary report of pathological changes of epiretinal membranes and internal limiting membrane removed during idiopathic macular hole surgery. / Li, Jiaqing; Tang, Shibo; Luo, Yan; Zhang, Jie; Lin, Shaofen.

In: Yan ke xue bao = Eye science / "Yan ke xue bao" bian ji bu, Vol. 18, No. 3, 01.01.2002, p. 143-146.

Research output: Contribution to journalArticle

@article{93f09a9a703346d5957ea283be09c48d,
title = "The preliminary report of pathological changes of epiretinal membranes and internal limiting membrane removed during idiopathic macular hole surgery.",
abstract = "PURPOSE: To investigate the pathological changes of epiretinal membranes (ERM) and internal limiting membrane (ILM) removed during idiopathic macular hole surgery. METHODS: Ten consecutive patients with a unilateral idiopathic macular hole underwent pars plana vitrectomy (PPV) with the surgical removal of the ERMs overlying the hole and ILM surrounding the hole. The pathological features of the excised tissues were examined under the microscope. RESULTS: According to the morphological changes, four ERMs showed cellular elements which looked like glia cells, macrophages, plasma cells, lymphocytes and fibroblast cells. Two of the ILM appeared as transparent membranes without cellular elements. The other eight ILM showed cellular elements on the transparent membranes. CONCLUSION: Our study supports the hypothesis that the tangential traction of vitreous and proliferative cellular elements on the inner surface of ILM causes idiopathic macular holes. Removal of the posterior cortical vitreous, ILM and proliferative cellular tissue is a valid treatment for IMH.",
author = "Jiaqing Li and Shibo Tang and Yan Luo and Jie Zhang and Shaofen Lin",
year = "2002",
month = "1",
day = "1",
language = "English (US)",
volume = "18",
pages = "143--146",
journal = "Eye Science",
issn = "1000-4432",
publisher = "Sun Yat-sen University of Medical Sciences",
number = "3",

}

TY - JOUR

T1 - The preliminary report of pathological changes of epiretinal membranes and internal limiting membrane removed during idiopathic macular hole surgery.

AU - Li, Jiaqing

AU - Tang, Shibo

AU - Luo, Yan

AU - Zhang, Jie

AU - Lin, Shaofen

PY - 2002/1/1

Y1 - 2002/1/1

N2 - PURPOSE: To investigate the pathological changes of epiretinal membranes (ERM) and internal limiting membrane (ILM) removed during idiopathic macular hole surgery. METHODS: Ten consecutive patients with a unilateral idiopathic macular hole underwent pars plana vitrectomy (PPV) with the surgical removal of the ERMs overlying the hole and ILM surrounding the hole. The pathological features of the excised tissues were examined under the microscope. RESULTS: According to the morphological changes, four ERMs showed cellular elements which looked like glia cells, macrophages, plasma cells, lymphocytes and fibroblast cells. Two of the ILM appeared as transparent membranes without cellular elements. The other eight ILM showed cellular elements on the transparent membranes. CONCLUSION: Our study supports the hypothesis that the tangential traction of vitreous and proliferative cellular elements on the inner surface of ILM causes idiopathic macular holes. Removal of the posterior cortical vitreous, ILM and proliferative cellular tissue is a valid treatment for IMH.

AB - PURPOSE: To investigate the pathological changes of epiretinal membranes (ERM) and internal limiting membrane (ILM) removed during idiopathic macular hole surgery. METHODS: Ten consecutive patients with a unilateral idiopathic macular hole underwent pars plana vitrectomy (PPV) with the surgical removal of the ERMs overlying the hole and ILM surrounding the hole. The pathological features of the excised tissues were examined under the microscope. RESULTS: According to the morphological changes, four ERMs showed cellular elements which looked like glia cells, macrophages, plasma cells, lymphocytes and fibroblast cells. Two of the ILM appeared as transparent membranes without cellular elements. The other eight ILM showed cellular elements on the transparent membranes. CONCLUSION: Our study supports the hypothesis that the tangential traction of vitreous and proliferative cellular elements on the inner surface of ILM causes idiopathic macular holes. Removal of the posterior cortical vitreous, ILM and proliferative cellular tissue is a valid treatment for IMH.

UR - http://www.scopus.com/inward/record.url?scp=28744448806&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=28744448806&partnerID=8YFLogxK

M3 - Article

C2 - 15510742

AN - SCOPUS:28744448806

VL - 18

SP - 143

EP - 146

JO - Eye Science

JF - Eye Science

SN - 1000-4432

IS - 3

ER -