The relationship between suppression of acidity and gastric ulcer healing rates

Colin Howden, R. H. Hunt

Research output: Contribution to journalArticle

89 Citations (Scopus)

Abstract

We have investigated the relationship between the suppression of acidity by antisecretory drugs for the treatment of benign gastric ulcer and their corresponding ulcer-healing rates. For a variety of antisecretory drug regimens, there was a significant correlation between suppression of 24-h intragastric acidity and ulcer healing rates after 2, 4 and 8 weeks of treatment. There was a lesser degree of correlation between healing and suppression of nocturnal acidity and the association between suppression of acidity and gastric-ulcer healing rates was less marked than that previously described for duodenal ulcer.

Original languageEnglish (US)
Pages (from-to)25-33
Number of pages9
JournalAlimentary Pharmacology and Therapeutics
Volume4
Issue number1
StatePublished - 1990
Externally publishedYes

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Stomach Ulcer
Ulcer
Duodenal Ulcer
Pharmaceutical Preparations

All Science Journal Classification (ASJC) codes

  • Pharmacology (medical)
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

The relationship between suppression of acidity and gastric ulcer healing rates. / Howden, Colin; Hunt, R. H.

In: Alimentary Pharmacology and Therapeutics, Vol. 4, No. 1, 1990, p. 25-33.

Research output: Contribution to journalArticle

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