The role of gadolinium-DTPA-enhanced magnetic resonance imaging in presurgical evaluation for intractable partial epilepsy

James Wheless, R. E. Figueroa-Ortiz, E. F. Binet, D. W. King, B. B. Gallagher, A. M. Murro, H. F. Flanigin, J. R. Smith, M. M. Leveridge

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

In order to evaluate the diagnostic efficacy of gadolinium-DTPA (Gd-DTPA), we performed enhanced and unenhanced magnetic resonance imaging (MRI) of the head in 48 Phase I presurgical patients. Fifty-two percent had normal MRI (unenhanced and enhanced). Forty-eight percent had abnormal unenhanced MRI. Gd-DTPA MRI was helpful preoperatively in 57% of these patients. Gd-DTPA improves the diagnostic sensitivity of MRI and provides important additional information in the presurgical evaluation of patients with partial epilepsy only if the unenhanced MRI is abnormal.

Original languageEnglish (US)
Pages (from-to)95-101
Number of pages7
JournalJournal of Epilepsy
Volume4
Issue number2
DOIs
StatePublished - Jan 1 1991
Externally publishedYes

Fingerprint

Gadolinium DTPA
Partial Epilepsy
Magnetic Resonance Imaging
Drug Resistant Epilepsy
Head

All Science Journal Classification (ASJC) codes

  • Clinical Neurology
  • Neuroscience(all)

Cite this

The role of gadolinium-DTPA-enhanced magnetic resonance imaging in presurgical evaluation for intractable partial epilepsy. / Wheless, James; Figueroa-Ortiz, R. E.; Binet, E. F.; King, D. W.; Gallagher, B. B.; Murro, A. M.; Flanigin, H. F.; Smith, J. R.; Leveridge, M. M.

In: Journal of Epilepsy, Vol. 4, No. 2, 01.01.1991, p. 95-101.

Research output: Contribution to journalArticle

Wheless, J, Figueroa-Ortiz, RE, Binet, EF, King, DW, Gallagher, BB, Murro, AM, Flanigin, HF, Smith, JR & Leveridge, MM 1991, 'The role of gadolinium-DTPA-enhanced magnetic resonance imaging in presurgical evaluation for intractable partial epilepsy', Journal of Epilepsy, vol. 4, no. 2, pp. 95-101. https://doi.org/10.1016/S0896-6974(05)80067-2
Wheless, James ; Figueroa-Ortiz, R. E. ; Binet, E. F. ; King, D. W. ; Gallagher, B. B. ; Murro, A. M. ; Flanigin, H. F. ; Smith, J. R. ; Leveridge, M. M. / The role of gadolinium-DTPA-enhanced magnetic resonance imaging in presurgical evaluation for intractable partial epilepsy. In: Journal of Epilepsy. 1991 ; Vol. 4, No. 2. pp. 95-101.
@article{4363e0e114ed4f87a6b5cb5097a8b0fc,
title = "The role of gadolinium-DTPA-enhanced magnetic resonance imaging in presurgical evaluation for intractable partial epilepsy",
abstract = "In order to evaluate the diagnostic efficacy of gadolinium-DTPA (Gd-DTPA), we performed enhanced and unenhanced magnetic resonance imaging (MRI) of the head in 48 Phase I presurgical patients. Fifty-two percent had normal MRI (unenhanced and enhanced). Forty-eight percent had abnormal unenhanced MRI. Gd-DTPA MRI was helpful preoperatively in 57{\%} of these patients. Gd-DTPA improves the diagnostic sensitivity of MRI and provides important additional information in the presurgical evaluation of patients with partial epilepsy only if the unenhanced MRI is abnormal.",
author = "James Wheless and Figueroa-Ortiz, {R. E.} and Binet, {E. F.} and King, {D. W.} and Gallagher, {B. B.} and Murro, {A. M.} and Flanigin, {H. F.} and Smith, {J. R.} and Leveridge, {M. M.}",
year = "1991",
month = "1",
day = "1",
doi = "10.1016/S0896-6974(05)80067-2",
language = "English (US)",
volume = "4",
pages = "95--101",
journal = "Epilepsy Research",
issn = "0920-1211",
publisher = "Elsevier",
number = "2",

}

TY - JOUR

T1 - The role of gadolinium-DTPA-enhanced magnetic resonance imaging in presurgical evaluation for intractable partial epilepsy

AU - Wheless, James

AU - Figueroa-Ortiz, R. E.

AU - Binet, E. F.

AU - King, D. W.

AU - Gallagher, B. B.

AU - Murro, A. M.

AU - Flanigin, H. F.

AU - Smith, J. R.

AU - Leveridge, M. M.

PY - 1991/1/1

Y1 - 1991/1/1

N2 - In order to evaluate the diagnostic efficacy of gadolinium-DTPA (Gd-DTPA), we performed enhanced and unenhanced magnetic resonance imaging (MRI) of the head in 48 Phase I presurgical patients. Fifty-two percent had normal MRI (unenhanced and enhanced). Forty-eight percent had abnormal unenhanced MRI. Gd-DTPA MRI was helpful preoperatively in 57% of these patients. Gd-DTPA improves the diagnostic sensitivity of MRI and provides important additional information in the presurgical evaluation of patients with partial epilepsy only if the unenhanced MRI is abnormal.

AB - In order to evaluate the diagnostic efficacy of gadolinium-DTPA (Gd-DTPA), we performed enhanced and unenhanced magnetic resonance imaging (MRI) of the head in 48 Phase I presurgical patients. Fifty-two percent had normal MRI (unenhanced and enhanced). Forty-eight percent had abnormal unenhanced MRI. Gd-DTPA MRI was helpful preoperatively in 57% of these patients. Gd-DTPA improves the diagnostic sensitivity of MRI and provides important additional information in the presurgical evaluation of patients with partial epilepsy only if the unenhanced MRI is abnormal.

UR - http://www.scopus.com/inward/record.url?scp=0026335858&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026335858&partnerID=8YFLogxK

U2 - 10.1016/S0896-6974(05)80067-2

DO - 10.1016/S0896-6974(05)80067-2

M3 - Article

VL - 4

SP - 95

EP - 101

JO - Epilepsy Research

JF - Epilepsy Research

SN - 0920-1211

IS - 2

ER -