The role of inflammation and infection in preterm birth

Jamie A. Bastek, Luis M. Gómez, Michal A. Elovitz

Research output: Contribution to journalReview article

63 Citations (Scopus)

Abstract

Much emphasis in recent decades has been devoted to inflammation and infection as a premier causal mechanism of preterm birth. This article explores the epidemiologic, clinical, and animal data that exist to support this conceptual paradigm as well as proposed mechanisms through which to potentially mitigate the adversity of prematurity. Truly successful interventions are not likely to occur until the pathogenesis of preterm birth and the role of inflammation in causing not only parturition but also fetal and neonatal injury is fully elucidated.

Original languageEnglish (US)
Pages (from-to)385-406
Number of pages22
JournalClinics in Perinatology
Volume38
Issue number3
DOIs
StatePublished - Sep 1 2011

Fingerprint

Premature Birth
Inflammation
Infection
Parturition
Wounds and Injuries

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

Cite this

The role of inflammation and infection in preterm birth. / Bastek, Jamie A.; Gómez, Luis M.; Elovitz, Michal A.

In: Clinics in Perinatology, Vol. 38, No. 3, 01.09.2011, p. 385-406.

Research output: Contribution to journalReview article

Bastek, Jamie A. ; Gómez, Luis M. ; Elovitz, Michal A. / The role of inflammation and infection in preterm birth. In: Clinics in Perinatology. 2011 ; Vol. 38, No. 3. pp. 385-406.
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