The role of taurine in renal disorders

Xiaobin Han, Russell W. Chesney

Research output: Contribution to journalReview article

18 Citations (Scopus)

Abstract

This article examines the actions of taurine on models of renal dysfunction, the potential mechanisms of taurine action and the possible clinical significance of these findings. Our laboratory has written previously on the role of taurine in renal function and we have focused upon the normal physiology of the kidney and on the mechanisms and regulation of the renal transport of taurine. This review is a distinct change of emphasis in that we describe a number of studies which have evaluated various aspects of renal dysfunction, including hypertension and proteinuria, specific glomerular and tubular disorders, acute and chronic renal conditions, urinary tract conditions including infection and nephrolithiasis, and diabetic nephropathy. The subject of chronic kidney disease and renal transplantation will also be examined relative to b amino acid. The studies evaluated will be mainly recent ones, recognizing that older reviews of the role of this taurine in the kidney are available.

Original languageEnglish (US)
Pages (from-to)2249-2263
Number of pages15
JournalAmino Acids
Volume43
Issue number6
DOIs
StatePublished - Jan 1 2012

Fingerprint

Taurine
Kidney
Kidney Transplantation
Physiology
Nephrolithiasis
Diabetic Nephropathies
Urinary Tract
Chronic Renal Insufficiency
Proteinuria
Amino Acids
Hypertension
Infection

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Clinical Biochemistry
  • Organic Chemistry

Cite this

The role of taurine in renal disorders. / Han, Xiaobin; Chesney, Russell W.

In: Amino Acids, Vol. 43, No. 6, 01.01.2012, p. 2249-2263.

Research output: Contribution to journalReview article

Han, Xiaobin ; Chesney, Russell W. / The role of taurine in renal disorders. In: Amino Acids. 2012 ; Vol. 43, No. 6. pp. 2249-2263.
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